Literature DB >> 14508075

Classical chemotherapy: mechanisms, toxicities and the therapeutic window.

Vikas Malhotra1, Michael C Perry.   

Abstract

Chemotherapy can be best used by understanding the principles of pharmacology, tumor biology, cellular kinetics and drug resistance. Here we try to focus on the major classes of chemotherapeutic drugs, their mechanisms of action, toxicities; and the therapeutic window.

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Year:  2003        PMID： 14508075

Source DB:  PubMed          Journal:  Cancer Biol Ther        ISSN： 1538-4047            Impact factor:   4.742


  42 in total

1.  Precision cancer medicine: where to target?

Authors:  Qiang Yu; Jian Ding
Journal:  Acta Pharmacol Sin       Date:  2015-09-21       Impact factor: 6.150

Review 2.  Evolving concepts in cancer therapy through targeting sphingolipid metabolism.

Authors:  Jean-Philip Truman; Mónica García-Barros; Lina M Obeid; Yusuf A Hannun
Journal:  Biochim Biophys Acta       Date:  2013-12-30

3.  Mechanisms of resistance to anti-angiogenic therapy and development of third-generation anti-angiogenic drug candidates.

Authors:  Sonja Loges; Thomas Schmidt; Peter Carmeliet
Journal:  Genes Cancer       Date:  2010-01

Review 4.  MicroRNAs: master regulators of drug resistance, stemness, and metastasis.

Authors:  Umar Raza; Jitao David Zhang; Ozgür Sahin
Journal:  J Mol Med (Berl)       Date:  2014-02-09       Impact factor: 4.599

5.  Pharmacological vs. classical approaches in the design of first in man clinical drug trials.

Authors:  Cornelis A van den Bogert; Adam F Cohen; Hubert G M Leufkens; Joop M A van Gerven
Journal:  Br J Clin Pharmacol       Date:  2017-10-06       Impact factor: 4.335

Review 6.  Cancer stem cells and chemoresistance: The smartest survives the raid.

Authors:  Jihe Zhao
Journal:  Pharmacol Ther       Date:  2016-02-17       Impact factor: 12.310

7.  Targeting the efficacy of a dendrimer-based nanotherapeutic in heterogeneous xenograft tumors in vivo.

Authors:  Andrzej Myc; Jolanta Kukowska-Latallo; Peter Cao; Ben Swanson; Julianna Battista; Thomas Dunham; James R Baker
Journal:  Anticancer Drugs       Date:  2010-02       Impact factor: 2.248

8.  Procaspase-3 activation as an anti-cancer strategy: structure-activity relationship of procaspase-activating compound 1 (PAC-1) and its cellular co-localization with caspase-3.

Authors:  Quinn P Peterson; Danny C Hsu; David R Goode; Chris J Novotny; Ryan K Totten; Paul J Hergenrother
Journal:  J Med Chem       Date:  2009-09-24       Impact factor: 7.446

Review 9.  Therapy-induced chemoexosomes: Sinister small extracellular vesicles that support tumor survival and progression.

Authors:  Shyam K Bandari; Kaushlendra Tripathi; Sunil Rangarajan; Ralph D Sanderson
Journal:  Cancer Lett       Date:  2020-08-26       Impact factor: 8.679

Review 10.  Consequences of cancer treatments on adult hippocampal neurogenesis: implications for cognitive function and depressive symptoms.

Authors:  Gisele Pereira Dias; Ronan Hollywood; Mário Cesar do Nascimento Bevilaqua; Anna Claudia Domingos da Silveira da Luz; Robert Hindges; Antonio Egidio Nardi; Sandrine Thuret
Journal:  Neuro Oncol       Date:  2014-01-26       Impact factor: 12.300
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