OBJECTIVE: Prior research suggesting a relationship between pancreatic cancer and depression conducted on clinical populations has been subject to recall bias. We reexamined this association using longitudinal population-based data. METHODS: This was a retrospective cohort study using longitudinal insurance claims data. RESULTS: Men with mental disorders were more likely to develop pancreatic cancer than those without psychiatric claims (odds ratio 2.4, confidence interval 1.15-4.78). Depression more commonly preceded pancreatic cancer than it did other gastrointestinal malignancies (odds ratio 4.6, confidence interval 1.07-19.4) or all other cancers (odds ratio 4.1, confidence interval 1.05-16.0). CONCLUSIONS: Depression and pancreatic cancer are associated in the general population.
OBJECTIVE: Prior research suggesting a relationship between pancreatic cancer and depression conducted on clinical populations has been subject to recall bias. We reexamined this association using longitudinal population-based data. METHODS: This was a retrospective cohort study using longitudinal insurance claims data. RESULTS:Men with mental disorders were more likely to develop pancreatic cancer than those without psychiatric claims (odds ratio 2.4, confidence interval 1.15-4.78). Depression more commonly preceded pancreatic cancer than it did other gastrointestinal malignancies (odds ratio 4.6, confidence interval 1.07-19.4) or all other cancers (odds ratio 4.1, confidence interval 1.05-16.0). CONCLUSIONS:Depression and pancreatic cancer are associated in the general population.
Authors: Casey A Boyd; Jaime Benarroch-Gampel; Kristin M Sheffield; Yimei Han; Yong-Fang Kuo; Taylor S Riall Journal: Surgery Date: 2012-09 Impact factor: 3.982
Authors: Andrew D Boyd; Doris Brown; Chris Henrickson; Janet Hampton; Bin Zhu; Farideh Almani; Edgar Ben-Josef; Mark Zalupski; Diane M Simeone; Jeremy M G Taylor; Roseanne Armitage; Michelle Riba Journal: ScientificWorldJournal Date: 2012-05-22