Literature DB >> 14507754

Defining and measuring treatment outcome in unilateral amblyopia.

C E Stewart1, M J Moseley, A R Fielder.   

Abstract

AIM: To offer a critique of current methods of defining amblyopia treatment outcome and to examine alternative approaches.
METHOD: Literature appraisal and descriptive case presentations.
RESULTS: Currently, the outcome of amblyopia treatment is expressed as the number of acuity chart lines gained or, alternatively, achievement of an arbitrarily adopted level of visual acuity. As binocular vision is optimised with equal visual input from each eye the authors propose that the optimum outcome of amblyopia therapy is to achieve a visual acuity in the amblyopic eye equal to that of its fellow. In addition, improvement should be graded as the proportion of change in visual acuity with respect to the absolute potential for improvement (that is, that pertaining in the fellow eye at end of treatment).
CONCLUSIONS: There are two methods of appropriately describing the outcome of amblyopia treatment: firstly, by the difference in final visual acuity of amblyopic and fellow eye (residual amblyopia); secondly, the proportion of the deficit corrected.

Entities:  

Mesh:

Year:  2003        PMID: 14507754      PMCID: PMC1920768          DOI: 10.1136/bjo.87.10.1229

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  16 in total

1.  Occlusion for amblyopia: a comprehensive survey of outcome.

Authors:  F Hiscox; N Strong; J R Thompson; C Minshull; G Woodruff
Journal:  Eye (Lond)       Date:  1992       Impact factor: 3.775

2.  CSF interocular interactions in childhood ambylopia.

Authors:  N Wali; L E Leguire; G L Rogers; D L Bremer
Journal:  Optom Vis Sci       Date:  1991-02       Impact factor: 1.973

3.  Anisometropic and strabismic amblyopia in the age group 2 years and above: a prospective study of the results of treatment.

Authors:  J Lithander; J Sjöstrand
Journal:  Br J Ophthalmol       Date:  1991-02       Impact factor: 4.638

4.  Validity and reliability of visual acuity measurements.

Authors:  J E Lovie-Kitchin
Journal:  Ophthalmic Physiol Opt       Date:  1988       Impact factor: 3.117

Review 5.  Current trends in amblyopia therapy.

Authors:  J T Flynn; J C Cassady
Journal:  Ophthalmology       Date:  1978-05       Impact factor: 12.079

6.  Defective processing of motion-defined form in the fellow eye of patients with unilateral amblyopia.

Authors:  D E Giaschi; D Regan; S P Kraft; X H Hong
Journal:  Invest Ophthalmol Vis Sci       Date:  1992-07       Impact factor: 4.799

7.  Anisometropic amblyopia.

Authors:  P J Kutschke; W E Scott; R V Keech
Journal:  Ophthalmology       Date:  1991-02       Impact factor: 12.079

8.  Glasgow Acuity Cards: a new test for the measurement of letter acuity in children.

Authors:  P V McGraw; B Winn
Journal:  Ophthalmic Physiol Opt       Date:  1993-10       Impact factor: 3.117

9.  The sensitive period for strabismic amblyopia in humans.

Authors:  M Epelbaum; C Milleret; P Buisseret; J L Dufier
Journal:  Ophthalmology       Date:  1993-03       Impact factor: 12.079

10.  Esotropic children with amblyopia: effects of patching on acuity.

Authors:  A B Fulton; D L Mayer
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1988       Impact factor: 3.117

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  15 in total

1.  "Global" visual training and extent of transfer in amblyopic macaque monkeys.

Authors:  Lynne Kiorpes; Paul Mangal
Journal:  J Vis       Date:  2015       Impact factor: 2.240

2.  Interactive binocular treatment (I-BiT) for amblyopia: results of a pilot study of 3D shutter glasses system.

Authors:  N Herbison; S Cobb; R Gregson; I Ash; R Eastgate; J Purdy; T Hepburn; D MacKeith; A Foss
Journal:  Eye (Lond)       Date:  2013-06-28       Impact factor: 3.775

Review 3.  Occlusion for stimulus deprivation amblyopia.

Authors:  Aileen Antonio-Santos; Satyanarayana S Vedula; Sarah R Hatt; Christine Powell
Journal:  Cochrane Database Syst Rev       Date:  2014-02-06

Review 4.  Interventions for stimulus deprivation amblyopia.

Authors:  S Hatt; A Antonio-Santos; C Powell; S S Vedula
Journal:  Cochrane Database Syst Rev       Date:  2006-07-19

5.  Can human amblyopia be treated in adulthood?

Authors:  Andrew T Astle; Paul V McGraw; Ben S Webb
Journal:  Strabismus       Date:  2011-09

6.  Functional visual acuity in patients with successfully treated amblyopia: a pilot study.

Authors:  Sujin Hoshi; Takahiro Hiraoka; Junko Kotsuka; Yumiko Sato; Shinya Izumida; Atsuko Kato; Yuta Ueno; Shinichi Fukuda; Tetsuro Oshika
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2017-02-24       Impact factor: 3.117

7.  Visual function in low birthweight children.

Authors:  A R O'Connor; T J Stephenson; A Johnson; M J Tobin; S Ratib; M Moseley; A R Fielder
Journal:  Br J Ophthalmol       Date:  2004-09       Impact factor: 4.638

8.  Objectively monitored patching regimens for treatment of amblyopia: randomised trial.

Authors:  Catherine E Stewart; David A Stephens; Alistair R Fielder; Merrick J Moseley
Journal:  BMJ       Date:  2007-09-13

9.  Evaluation and development of a novel binocular treatment (I-BiT™) system using video clips and interactive games to improve vision in children with amblyopia ('lazy eye'): study protocol for a randomised controlled trial.

Authors:  Alexander J Foss; Richard M Gregson; Daisy MacKeith; Nicola Herbison; Isabel M Ash; Sue V Cobb; Richard M Eastgate; Trish Hepburn; Anthony Vivian; Diane Moore; Stephen M Haworth
Journal:  Trials       Date:  2013-05-20       Impact factor: 2.279

Review 10.  Binocular versus standard occlusion or blurring treatment for unilateral amblyopia in children aged three to eight years.

Authors:  Vijay Tailor; Manuela Bossi; Catey Bunce; John A Greenwood; Annegret Dahlmann-Noor
Journal:  Cochrane Database Syst Rev       Date:  2015-08-11
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