Literature DB >> 14495626

Assay of oxytocin by rat mammary gland in vitro.

G RYDEN, I SJOHOLM.   

Abstract

A new method for quantitative assay of oxytocin using strips from rat mammary gland in vitro has been investigated. The method is very suitable for determination of small amounts of oxytocin. Doses down to 2 mu-u. oxytocin have been estimated. The dose-response curve is shown to be linear, and the precision of the method is good (lambda =0.10 to 0.14). The effect of adrenaline, noradrenaline, acetylcholine, histamine and 5-hydroxytryptamine on the rat mammary gland has also been tested.

Entities:  

Keywords:  BIOLOGICAL ASSAY; BREAST/pharmacology; OXYTOCICS/chemistry

Mesh：

Substances：

Year:  1962        PMID： 14495626      PMCID： PMC1482239          DOI： 10.1111/j.1476-5381.1962.tb01434.x

Source DB:  PubMed          Journal:  Br J Pharmacol Chemother        ISSN： 0366-0826


  3 in total

1.  Improved method for quantitative estimation of oxytocin.

Authors:  I SJOHOLM; G RYDEN
Journal:  Nature       Date:  1962-01-06       Impact factor: 49.962

2.  The technique of superfusion.

Authors:  J H GADDUM
Journal:  Br J Pharmacol Chemother       Date:  1953-09

3.  New Test for the Biological Assay of Oxytocin.

Authors:  C Mendez-Bauer; H M Cabot; R Caldeyro-Barcia
Journal:  Science       Date:  1960-07-29       Impact factor: 47.728
  3 in total
  8 in total

1.  Bioassay of oxytocin on the superfused mammary gland of the mouse, using an automatic apparatus.

Authors:  I C Robinson; J M Walker
Journal:  Br J Pharmacol       Date:  1974-03       Impact factor: 8.739

2.  A sensitive method for the assay of oxytocin in the circulating blood.

Authors:  J R Vane; K I Williams
Journal:  Br J Pharmacol       Date:  1974-10       Impact factor: 8.739

3.  A simple double-pulse isolation unit for use with a students' nerve stimulator.

Authors:  W Barry; H E Davies
Journal:  J Physiol       Date:  1968-03       Impact factor: 5.182

4.  Hydroxy analogues of oxytocin and of lysine-vasopressin.

Authors:  G W Bisset; H S Chowdrey; D B Hope; N Nilwises; M Wälti
Journal:  Br J Pharmacol       Date:  1979-12       Impact factor: 8.739

5.  Synthetic analogues of oxytocin acting as hormonogens.

Authors:  Z Beránková-Ksandrová; G W Bisset; K Jost; I Krejci; V Pliska; J Rudinger; I Rychlík; F Sorm
Journal:  Br J Pharmacol Chemother       Date:  1966-03

6.  Some pharmacological properties of a synthetic oxytocin analogue [1-N-carbamoyl-hemicystine-2-O-methyltyrosine]-oxytocin (carbamoyl-methyloxytocin), an antagonist to the neurohypophysial hormones.

Authors:  G W Bisset; B J Clark; I Krejcí; I Polácek; J Rudinger
Journal:  Br J Pharmacol       Date:  1970-10       Impact factor: 8.739

7.  The clearance and antidiuretic potency of neurohypophysial hormones in man, and their plasma binding and stability.

Authors:  M Fabian; M L Forsling; J J Jones; J S Pryor
Journal:  J Physiol       Date:  1969-10       Impact factor: 5.182

8.  The response of the human myometrium to 5-hydroxytryptamine (5-HT) and oxytocin (Syntocinon) and its monoamine oxidase (MAO) activity during gestation.

Authors:  S F Contractor; J J Jones; J Lee; N F Morris
Journal:  J Physiol       Date:  1968-03       Impact factor: 5.182
  8 in total

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