Literature DB >> 1449054

Three human osteosarcoma cell lines exhibiting different phenotypic expressions.

T Hotta1, T Motoyama, H Watanabe.   

Abstract

to elucidate the differences in histological features and biological behavior of osteosarcomas, three human osteoblastic-type osteosarcomas were studied in vitro and in nude mice. The secretory processing and extracellular fiber formation of type I collagen proved to be the most important factor in bone formation in the osteosarcomas. Alkaline phosphatase also seemed to be important. However, we were unable to find any particular protooncogene abnormalities which could have been implicated in the occurrence or biological behavior of these osteosarcomas.

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Year:  1992        PMID： 1449054     DOI： 10.1111/j.1440-1827.1992.tb03110.x

Source DB:  PubMed          Journal:  Acta Pathol Jpn        ISSN： 0001-6632


  11 in total

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2.  Effect of temozolomide on the viability of musculoskeletal sarcoma cells.

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4.  Bone formation in vitro and in nude mice by human osteosarcoma cells.

Authors:  A Ogose; T Motoyama; T Hotta; H Watanabe; H E Takahashi
Journal:  Virchows Arch       Date:  1995       Impact factor: 4.064

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10.  Biological safety of fish (tilapia) collagen.

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