Literature DB >> 1448059

Effect of ethanol on hepatic ribosomal proteins and mRNA.

K S Haviryaji1, R Srinivas, T Suryanarayana, M C Vemuri.   

Abstract

Levels of RNA, mRNA and separation of ribosomal proteins from control and ethanol treated rat liver, showed no change in total RNA content, but poly(A+)mRNA was reduced significantly in ethanolic rats. Ribosomal proteins S2, S3a, S3b, S4, L3, L4, L4a, L10a and L15 were found substantially reduced in experimental rat livers. This study suggests decrease in poly(A+) mRNA coupled with loss of ribosomal proteins must be responsible for decreased protein synthesis in chronic alcoholism.

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Year:  1992        PMID： 1448059     DOI： 10.1007/bf00230324

Source DB:  PubMed          Journal:  Mol Cell Biochem        ISSN： 0300-8177            Impact factor:   3.396


  18 in total

1.  Differences in the plasma membrane proteins of chronic alcoholic rat brain.

Authors:  P P Babu; N Nagaraju; M C Vemuri
Journal:  Membr Biochem       Date:  1990 Jul-Sep

Review 2.  Translational dynamics. Interactions between the translational factors, tRNA and ribosomes during eukaryotic protein synthesis.

Authors:  O Nygård; L Nilsson
Journal:  Eur J Biochem       Date:  1990-07-20

3.  Liver plasma membrane proteins in chronic ethanol intoxication.

Authors:  P P Babu; M C Vemuri
Journal:  Biochem Int       Date:  1990

4.  The effect of ethanol and haloperidol on dopamine receptor (D2) density.

Authors:  V Fuchs; H Coper; H Rommelspacher
Journal:  Neuropharmacology       Date:  1987-08       Impact factor: 5.250

5.  Experimental alcoholism in rats. Effect of acute ethanol intoxication on the in vitro incorporation of ( 3 H)leucine into neuronal and glial proteins.

Authors:  J Jarlstedt; A Hamberger
Journal:  J Neurochem       Date:  1972-10       Impact factor: 5.372

6.  Spot position of rat liver ribosomal proteins by four different two-dimensional electrophoreses in polyacrylamide gel.

Authors:  J J Madjar; M Arpin; M Buisson; J P Reboud
Journal:  Mol Gen Genet       Date:  1979-03-20

7.  Inhibition of protein synthesis by ethanol in isolated rat liver parenchymal cells.

Authors:  J Mørland; A Bessesen
Journal:  Biochim Biophys Acta       Date:  1977-01-20

8.  An improved method for two-dimensional gel-electrophoresis: analysis of mutationally altered ribosomal proteins of Escherichia coli.

Authors:  D Geyl; A Böck; K Isono
Journal:  Mol Gen Genet       Date:  1981

9.  The role of glucose and insulin in the effect of ethanol on protein synthesis in isolated rat hepatocytes.

Authors:  B Wallin; J Mørland
Journal:  Alcohol Alcohol       Date:  1987       Impact factor: 2.826

10.  Studies on the effects of chronic ethanol ingestion on the properties of rat brain ribosomes.

Authors:  S Tewari; S Murray; E P Noble
Journal:  J Neurosci Res       Date:  1978       Impact factor: 4.164
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  4 in total

1.  Effect of ethanol on nuclear casein kinase II activity in brain.

Authors:  K S Haviryaji; M C Vemuri
Journal:  Neurochem Res       Date:  1997-06       Impact factor: 3.996

2.  Effect of ethanol on chromatin and nonhistone nuclear proteins in rat brain.

Authors:  K Mahadev; M C Vemuri
Journal:  Neurochem Res       Date:  1998-09       Impact factor: 3.996

3.  Ethanol induced alterations in plasma membrane protein phosphorylation of neurons and astrocytes.

Authors:  P P Babu; L R Kumari; M C Vemuri
Journal:  Mol Cell Biochem       Date:  1994-01-12       Impact factor: 3.396

4.  Differential changes in cell morphology, macromolecular composition and membrane protein profiles of neurons and astrocytes in chronic ethanol treated rats.

Authors:  P P Babu; L R Kumari; M C Vemuri
Journal:  Mol Cell Biochem       Date:  1994-01-12       Impact factor: 3.396
  4 in total

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