Literature DB >> 14412415

The error hypothesis of mutation.

H E KUBITSCHEK.   

Abstract

Accumulation of mutants in glucose-limited chemostats is proportional to growth rate, while in tryptophan-limited chemostats it is independent of growth rate. This behavior, which implies the failure of the error hypothesis, may be explainable on the basis of a unitary hypothesis: the results with glucose may be due to reversion or loss of latent mutants.

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Keywords:  GENETICS

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Year:  1960        PMID： 14412415     DOI： 10.1126/science.131.3402.730

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  3 in total

1.  Mutagenesis by mutator gene mutH1 in continuous cultures of Escherichia coli.

Authors:  E R Nestmann; R F Hill
Journal:  J Bacteriol       Date:  1974-07       Impact factor: 3.490

2.  Participation of the intracellular enzymes in the control of the mutation process : III. Influence of the inhibition of repair and replication on γ-ray induced chromosomal aberrations in barley.

Authors:  V N Soyfer; N A Kartel
Journal:  Theor Appl Genet       Date:  1978-01       Impact factor: 5.699

3.  MUTATION IN CONTINUOUS CULTURES. 3. MUTATIONAL RESPONSES IN ESCHERICHIA COLI.

Authors:  H E KUBITSCHEK; L A GUSTAFSON
Journal:  J Bacteriol       Date:  1964-12       Impact factor: 3.490
  3 in total

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