Literature DB >> 14406750

Chemistry and pharmacology of CNS depressants related to 4-(4-hydroxy-phenylpiperidino)butyrophenone. I. Synthesis and screening data in mice.

P A JANSSEN, C VAN DE WESTERINGH, A H JAGENEAU, P J DEMOEN, B K HERMANS, G H VAN DAELE, K H SCHELLEKENS, C A VAN DER EYCKEN.   

Abstract

Entities:  

Keywords:  CENTRAL NERVOUS SYSTEM/pharmacology; KETONE BODIES/chemistry; KETONE BODIES/pharmacology

Mesh：

Substances：

Year:  1959        PMID： 14406750     DOI： 10.1021/jm50004a007

Source DB:  PubMed          Journal:  J Med Pharm Chem        ISSN： 0095-9065


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  8 in total

Review 1.  Pharmacology and biochemistry of haloperidol.

Authors:  C J Niemegeers; P M Laduron
Journal:  Proc R Soc Med       Date:  1976

2.  The rapid control of the acute patient by haloperidol.

Authors:  A J Oldham
Journal:  Proc R Soc Med       Date:  1976

Review 3.  The pharmacological and biochemical basis of neuroleptic treatment in schizophrenia.

Authors:  C J Niemegeers; J E Leysen
Journal:  Pharm Weekbl Sci       Date:  1982-06-25

4.  Structure-based design of nonpeptide inhibitors specific for the human immunodeficiency virus 1 protease.

Authors:  R L DesJarlais; G L Seibel; I D Kuntz; P S Furth; J C Alvarez; P R Ortiz de Montellano; D L DeCamp; L M Babé; C S Craik
Journal:  Proc Natl Acad Sci U S A       Date:  1990-09       Impact factor: 11.205

5.  Bromperidol, a new butyrophenone neuroleptic: a review.

Authors:  B Dubinsky; J L McGuire; C J Niemegeers; P A Janssen; H S Weintraub; B E McKenzie
Journal:  Psychopharmacology (Berl)       Date:  1982       Impact factor: 4.530

6.  Effect of triperidol on carbohydrate and amino acid metabolism in rat brain-cortex slices.

Authors:  H Michalek; G L Gatti; F Pocchiari
Journal:  Biochem J       Date:  1968-11       Impact factor: 3.857

7.  Metabolic studies on haloperidol and its tetrahydropyridinyl dehydration product (HPTP) in C57BL/6 mouse brain preparations.

Authors:  Etsuko Usuki; Jeffrey R Bloomquist; Ethan Freeborn; Kay Casagnoli; Cornelis J Van Der Schyf; Neal Castagnoli
Journal:  Neurotox Res       Date:  2002-02       Impact factor: 3.911

Review 8.  History of the dopamine hypothesis of antipsychotic action.

Authors:  Mary V Seeman
Journal:  World J Psychiatry       Date:  2021-07-19
  8 in total

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