Literature DB >> 14328038

HUMAN BOTULISM DUE TO COMMERCIAL PRODUCTS.

R W REED, C A BUTAS, R J GALL.   

Abstract

Two cases of botulism occurred in Montreal following the ingestion of commercially canned liver paste. A toxigenic, proteolytic strain of Clostridium botulinum type B was isolated from the paste in which type B toxin was also demonstrated by animal protection tests. One patient died undiagnosed about 45 hours after eating several liver-paste sandwiches. The second developed diplopia, dysphagia, speech difficulty and weakness 18 hours after ingestion of three bites of a sandwich. All symptoms progressed until admission to hospital where he was treated with 160,000 units of divalent botulinum AB antitoxin over a 72-hour period. Recovery was complete. The need for readily available supplies of both diagnostic and therapeutic botulinum antitoxin to meet such an emergency is stressed.

Entities:  

Keywords:  ADOLESCENCE; BOTULISM; CANADA; DIAGNOSIS; EPIDEMIOLOGY; FOOD CONTAMINATION; TOXICOLOGIC REPORT; TOXINS AND ANTITOXINS

Mesh:

Substances:

Year:  1965        PMID: 14328038      PMCID: PMC1928669     

Source DB:  PubMed          Journal:  Can Med Assoc J        ISSN: 0008-4409            Impact factor:   8.262


  6 in total

1.  STATUS OF BOTULISM IN THE UNITED STATES.

Authors:  B J OSHEROFF; G G SLOCUM; W M DECKER
Journal:  Public Health Rep       Date:  1964-10       Impact factor: 2.792

2.  BOTULISM, VINTAGE 1963.

Authors:  D E ROGERS
Journal:  Ann Intern Med       Date:  1964-09       Impact factor: 25.391

3.  BOTULISM, TYPE E; REPORT OF EIGHT SIMULTANEOUS CASES.

Authors:  R L WHITTAKER; R B GILBERTSON; A S GARRETT
Journal:  Ann Intern Med       Date:  1964-09       Impact factor: 25.391

Review 4.  BOTULISM: THE DISEASE AND THE TOXIN.

Authors:  C S PETTY
Journal:  Am J Med Sci       Date:  1965-03       Impact factor: 2.378

5.  Further outbreaks of botulism in Canada.

Authors:  C E DOLMAN
Journal:  Can Med Assoc J       Date:  1961-01-28       Impact factor: 8.262

6.  Fish eggs as a cause of human botulism. Two outbreaks in British Columbia due to types E and B botulinus toxins.

Authors:  C E DOLMAN; M TOMSICH; C C CAMPBELL; W B LAING
Journal:  J Infect Dis       Date:  1960 Jan-Feb       Impact factor: 5.226

  6 in total
  2 in total

1.  Observations on the microbiological flora of canned Parma ham.

Authors:  J Cragg; A V Andrews
Journal:  J Hyg (Lond)       Date:  1973-06

2.  Human botulism in Canada (1919-1973).

Authors:  C E Dolman
Journal:  Can Med Assoc J       Date:  1974-01-19       Impact factor: 8.262

  2 in total

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