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Literature DB >> 14316950

THE ISOLATION AND BIOLOGICAL ACTIVITIES OF RABBIT GAMMA M- AND GAMMA G-ANTI-SALMONELLA TYPHIMURIUM ANTIBODIES.

Abstract

Rabbit gammaM- and gammaG-anti-S. typhimurium antibodies were isolated by combined immune specific and physical methods and some of their properties in immunological systems were measured. gammaM-Antibody was detectable at lower concentrations and revealed a higher specific activity than the gammaG-globulins. Indirect studies indicated that the gammaG-globulin was the more "avid" immunoglobulin. Treatment of the gammaM-globulin with the reducing agent 2-ME decreased but did not destroy the immune activity of the subunits. The results confirm the necessity of analysis of purified immunoglobulin antibodies to evaluate the significance of their biological properties secondary to their interaction with antigens.

Entities: Chemical Species

Keywords: AGGLUTINATION; ANTIBODIES; EXPERIMENTAL LAB STUDY; GAMMA GLOBULIN; PHAGOCYTOSIS; RABBITS; SALMONELLA TYPHIMURIUM

Mesh：

Substances：

Year: 1965 PMID： 14316950 PMCID： PMC2138065 DOI： 10.1084/jem.122.2.385

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

29 in total

1. SOME ASPECTS OF THE ANTIBODY RESPONSE OF RABBITS TO IMMUNIZATION WITH ENTEROBACTERIAL SOMATIC ANTIGENS.

Authors: W P WEIDANZ; A L JACKSON; M LANDY
Journal: Proc Soc Exp Biol Med Date: 1964-07

2. MULTIPLICITY OF ANTIBODY PROTEINS IN RABBIT ANTI-P-AZOBENZENEARSONATE SERA.

Authors: K ONOUE; Y YAGI; D PRESSMAN
Journal: J Immunol Date: 1964-02 Impact factor: 5.422

3. CHARACTERIZATION OF HUMAN ANTIBODIES TO SALMONELLA TYPHI BY GEL-FILTRATION AND ANTIGENIC ANALYSIS.

Authors: M W TURNER; D S ROWE
Journal: Immunology Date: 1964-11 Impact factor: 7.397

4. The complement-fixing properties of gamma1 and gamma2 rabbit anti-sheep hemolytic antibodies.

Authors: H S GOODMAN; L MASAITIS
Journal: J Infect Dis Date: 1960 Nov-Dec Impact factor: 5.226

5. Antibodies in the rabbit with different rates of metabolic decay.

Authors: W H TALIAFERRO; D W TALMAGE
Journal: J Infect Dis Date: 1956 Jul-Aug Impact factor: 5.226

6. Quantitative studies on the bactericidal actions of serum and complement. II. Some implications for the mechanism of the bactericidal reaction.

Authors: L H MUSCHEL; H P TREFFERS
Journal: J Immunol Date: 1956-01 Impact factor: 5.422

7. The formation of macroglobulin antibodies. I. Studies on adult humans.

Authors: J LOSPALLUTO; W MILLER; B DORWARD; C W FINK
Journal: J Clin Invest Date: 1962-07 Impact factor: 14.808

8. VALENCE AND AFFINITY OF EQUINE NONPRECIPITATING ANTIBODY TO A HAPTENIC GROUP.

Authors: N R KLIMAN; J H ROCKEY; F KARUSH
Journal: Science Date: 1964-10-16 Impact factor: 47.728

9. ACTIVITY OF DISSOCIATED AND REASSOCIATED 19S ANTI-GAMMA-GLOBULINS.

Authors: R E SCHROHENLOHER; H G KUNKEL; T B TOMASI
Journal: J Exp Med Date: 1964-12-01 Impact factor: 14.307

10. Studies on fluorescent antibody staining. I. Non-specific fluorescence with fluorescein-coupled sheep anti-rabbit globulins.

Authors: G GOLDSTEIN; I S SLIZYS; M W CHASE
Journal: J Exp Med Date: 1961-07-01 Impact factor: 14.307

78 in total

1. The in vitro and in vivo effects of carrageenin on humoral and cellular factors of natural resistance.

Authors: I Miler; A Stelzner
Journal: Folia Microbiol (Praha) Date: 1975 Impact factor: 2.099

2. Antibodies-structure and biological function.

Authors: J H Humphrey
Journal: Proc R Soc Med Date: 1967-06

3. Dog immunoglobulins. II. The antibacterial properties of dog IgA, IgM and IgG antibodies to Vibrio cholerae.

Authors: R J Heddle; D Rowley
Journal: Immunology Date: 1975-07 Impact factor: 7.397

4. Comparing the roles of antibodies to nontyphoidal Salmonella enterica in high- and low-income countries and implications for vaccine development.

Authors: Calman A MacLennan; Sharon M Tennant
Journal: Clin Vaccine Immunol Date: 2013-07-31

5. Specific secondary biological properties of purified rabbit immunoglobulin M and immunoglobulin G antibodies to Brucella abortus and Bordetella pertussis.

Authors: M L Schulkind; M Herzberg; J B Robbins
Journal: Infect Immun Date: 1971-09 Impact factor: 3.441

6. Characterization of "clearance" factor and "cell-bound" antibody in experimental typhoid.

Authors: D Ushiba; T Nakae; T Akiyama; Y Kishimoto
Journal: J Bacteriol Date: 1966-05 Impact factor: 3.490

7. Functional properties of isotype-switched immunoglobulin M (IgM) and IgG monoclonal antibodies to Pseudomonas aeruginosa lipopolysaccharide.

Authors: M Pollack; N L Koles; M J Preston; B J Brown; G B Pier
Journal: Infect Immun Date: 1995-11 Impact factor: 3.441

8. Neutralization of tetanus toxin by human and rabbit immunoglobulin classes and subunits.

Authors: D D Ourth; A B MacDonald
Journal: Immunology Date: 1977-12 Impact factor: 7.397

9. An assay for determining the relative affinity of trace amounts of labeled antibodies.

Authors: L A Steiner; H N Eisen
Journal: J Exp Med Date: 1967-12-01 Impact factor: 14.307

10. Heterogeneity of antibody response to Salmonella lipopolysaccharide measured by passive hemagglutination and hemolysis in mice.

Authors: J P Ransom; C Larson; J M Gorman; S Tulve
Journal: J Bacteriol Date: 1968-10 Impact factor: 3.490