Literature DB >> 14186463

VALENCE AND AFFINITY OF EQUINE NONPRECIPITATING ANTIBODY TO A HAPTENIC GROUP.

N R KLIMAN, J H ROCKEY, F KARUSH.   

Abstract

A nonprecipitable antibody to a haptenic group has been purified from equine serum. It is a 7S beta2delta immunoglobulin with high affinity for the specific hapten and two binding sites per antibody molecule. These results rule out univalence and low affinity as explanations of the nonprecipitability of this antibody.

Entities:  

Keywords:  ANTIBODIES; EXPERIMENTAL LAB STUDY; GAMMA GLOBULIN; HAPTENS; HORSES

Mesh：

Substances：

Year:  1964        PMID： 14186463     DOI： 10.1126/science.146.3642.401

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  9 in total

1.  Biological and physicochemical properties of purified anti-DNP guinea-pig non-precipitating antibodies.

Authors:  R A Margni; S Hajos
Journal:  Immunology       Date:  1973-03       Impact factor: 7.397

2.  Purification and properties of non-precipitating rabbit antibodies.

Authors:  R Margni; R Binaghi
Journal:  Immunology       Date:  1972-04       Impact factor: 7.397

3.  Studies on the IgA system of the horse.

Authors:  J P Vaerman; P Querinjean; J F Heremans
Journal:  Immunology       Date:  1971-09       Impact factor: 7.397

4.  Non-precipitating rabbit antibody to hapten: purification and properties.

Authors:  B G Carter; T N Harris
Journal:  Immunology       Date:  1967-01       Impact factor: 7.397

5.  Studies on equine immunoglobulins. IV. Immunoglobulins of the donkey.

Authors:  P Z Allen; E J Dalton
Journal:  Immunology       Date:  1975-01       Impact factor: 7.397

6.  Functional properties of bovine IgG1 and IgG2: interaction with complement, macrophages, neutrophils and skin.

Authors:  T C McGuire; A J Musoke; T Kurtti
Journal:  Immunology       Date:  1979-10       Impact factor: 7.397

7.  Distinct functions of monoclonal IgG antibody depend on antigen-site specificities.

Authors:  W Schalch; J K Wright; L S Rodkey; D G Braun
Journal:  J Exp Med       Date:  1979-04-01       Impact factor: 14.307

8.  THE ISOLATION AND BIOLOGICAL ACTIVITIES OF RABBIT GAMMA M- AND GAMMA G-ANTI-SALMONELLA TYPHIMURIUM ANTIBODIES.

Authors:  J B ROBBINS; K KENNY; E SUTER
Journal:  J Exp Med       Date:  1965-08-01       Impact factor: 14.307

9.  Equine antihapten antibody. The subunits and fragments of anti-beta-lactoside antibody.

Authors:  J H Rockey
Journal:  J Exp Med       Date:  1967-02-01       Impact factor: 14.307
  9 in total

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