Literature DB >> 1429226

Reveromycins, new inhibitors of eukaryotic cell growth. II. Biological activities.

H Takahashi1, H Osada, H Koshino, M Sasaki, R Onose, M Nakakoshi, M Yoshihama, K Isono.   

Abstract

Reveromycins A, B, C and D showed inhibitory activity against EGF-stimulated mitogen response in Balb/MK cells. Furthermore reveromycins A, C and D exhibited morphological reversion of srcts-NRK cells, antiproliferative activity against human tumor cell lines and antifungal activity. The effects of reveromycins A, C and D on eukaryotic cells were closely similar to each other, but those of reveromycin B were very weak. In vitro studies revealed that reveromycin A is a selective inhibitor of protein synthesis in eukaryotic cells.

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Year:  1992        PMID： 1429226     DOI： 10.7164/antibiotics.45.1414

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  9 in total

1.  Garbled messages and corrupted translations.

Authors:  Tilman Schneider-Poetsch; Takeo Usui; Daisuke Kaida; Minoru Yoshida
Journal:  Nat Chem Biol       Date:  2010-03       Impact factor: 15.040

Review 2.  Chemical and biological studies of reveromycin A.

Authors:  Hiroyuki Osada
Journal:  J Antibiot (Tokyo)       Date:  2016-06-08       Impact factor: 2.649

3.  Reveromycin A biosynthesis uses RevG and RevJ for stereospecific spiroacetal formation.

Authors:  Shunji Takahashi; Atsushi Toyoda; Yasuyo Sekiyama; Hiroshi Takagi; Toshihiko Nogawa; Masakazu Uramoto; Ryuichiro Suzuki; Hiroyuki Koshino; Takuto Kumano; Suresh Panthee; Tohru Dairi; Jun Ishikawa; Haruo Ikeda; Yoshiyuki Sakaki; Hiroyuki Osada
Journal:  Nat Chem Biol       Date:  2011-06-05       Impact factor: 15.040

4.  Enantioselective total synthesis of spirofungins A and B.

Authors:  Michael T Crimmins; Elizabeth A O'Bryan
Journal:  Org Lett       Date:  2010-10-01       Impact factor: 6.005

5.  Reveromycin A, an agent for osteoporosis, inhibits bone resorption by inducing apoptosis specifically in osteoclasts.

Authors:  Je-Tae Woo; Makoto Kawatani; Masanori Kato; Toshimasa Shinki; Takayuki Yonezawa; Naoki Kanoh; Hiroshi Nakagawa; Masamichi Takami; Kun Hyung Lee; Paula H Stern; Kazuo Nagai; Hiroyuki Osada
Journal:  Proc Natl Acad Sci U S A       Date:  2006-03-13       Impact factor: 11.205

6.  Reveromycins A and B from Streptomyces sp. 3-10: Antifungal Activity against Plant Pathogenic Fungi In vitro and in a Strawberry Food Model System.

Authors:  Ang Lyu; Hao Liu; Hongjie Che; Long Yang; Jing Zhang; Mingde Wu; Weidong Chen; Guoqing Li
Journal:  Front Microbiol       Date:  2017-04-03       Impact factor: 5.640

7.  Biocontrol of Aspergillus flavus on Peanut Kernels Using Streptomyces yanglinensis 3-10.

Authors:  Qaiser Shakeel; Ang Lyu; Jing Zhang; Mingde Wu; Guoqing Li; Tom Hsiang; Long Yang
Journal:  Front Microbiol       Date:  2018-05-23       Impact factor: 5.640

Review 8.  Asymmetric synthesis of naturally occurring spiroketals.

Authors:  B Rama Raju; Anil K Saikia
Journal:  Molecules       Date:  2008-08-28       Impact factor: 4.411

9.  β-carboline biomediators induce reveromycin production in Streptomyces sp. SN-593.

Authors:  Suresh Panthee; Shunji Takahashi; Teruo Hayashi; Takeshi Shimizu; Hiroyuki Osada
Journal:  Sci Rep       Date:  2019-04-09       Impact factor: 4.379
  9 in total

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