Literature DB >> 14276159

DETECTION OF FORMIMINO-GLUTAMIC AND UROCANIC ACIDS IN URINE BY MEANS OF THIN-LAYER CHROMATOGRAPHY.

M ROBERTS, S D MOHAMED.   

Abstract

A simple and rapid method has been developed for the simultaneous separation and semi-quantitative estimation of formimino-glutamic and urocanic acids in urine. The urinary excretion of these compounds in a group of normal subjects and in a number of illustrative cases has been determined. In view of current opinion that it is the total of these two metabolites of histidine which is the significant figure in clinical investigation, their simultaneous separation and measurement is an important advantage of the method.

Entities:  

Keywords:  AMINO ACID METABOLISM; AMINO ACIDS; CHROMATOGRAPHY; CLINICAL RESEARCH; FIGLU TEST; GLUTAMATES; HISTIDINE; IMIDAZOLES; URINE

Mesh：

Substances：

Year:  1965        PMID： 14276159      PMCID： PMC472870          DOI： 10.1136/jcp.18.2.214

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  12 in total

1.  Urocanic acid and formimino-glutamic acid excretion in megaloblastic anaemia and other conditions: the effect of specific therapy.

Authors:  I CHANARIN
Journal:  Br J Haematol       Date:  1963-04       Impact factor: 6.998

2.  Urinary excretion of urocanic acid and formimino-glutamic acid.

Authors:  M C BENNETT; I CHANARIN
Journal:  Nature       Date:  1962-10-20       Impact factor: 49.962

3.  Amino-acid and protein metabolism in pernicious anaemia.

Authors:  D W NEILL; J A WEAVER
Journal:  Br J Haematol       Date:  1958-10       Impact factor: 6.998

4.  Observations on the aminoaciduria in megaloblastic anaemia.

Authors:  D TODD
Journal:  J Clin Pathol       Date:  1959-05       Impact factor: 3.411

5.  Simplified method for detecting formiminoglutamic acid in urine as a test of folic-acid deficiency.

Authors:  J P KNOWLES; T A PRANKERD; R G WESTALL
Journal:  Lancet       Date:  1960-08-13       Impact factor: 79.321

6.  A method for the determination of formiminoglutamic acid in urine.

Authors:  H TABOR; L WYNGARDEN
Journal:  J Clin Invest       Date:  1958-06       Impact factor: 14.808

7.  A method for the detection of N-formiminoglutamic acid in urine.

Authors:  M SILVERMAN; R C GARDINER; P T CONDIT
Journal:  J Natl Cancer Inst       Date:  1958-01       Impact factor: 13.506

8.  The enzymatic degradation of histidine.

Authors:  B A BOREK; H WAELSCH
Journal:  J Biol Chem       Date:  1953-11       Impact factor: 5.157

9.  Influence of succinylsulfathiazole and folic acid on glutamic acid excretion.

Authors:  H A BAKERMAN; M SILVERMAN; F S DAFT
Journal:  J Biol Chem       Date:  1951-01       Impact factor: 5.157

10.  Conventional voltage electrophoresis for formiminoglutamic-acid determination in folic acid deficiency.

Authors:  J KOHN; D L MOLLIN; L M ROSENBACH
Journal:  J Clin Pathol       Date:  1961-07       Impact factor: 3.411
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