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Literature DB >> 13757596

Conventional voltage electrophoresis for formiminoglutamic-acid determination in folic acid deficiency.

Abstract

A new method for the determination of urinary formiminoglutamic acid (FIGLU) using conventional electrophoresis at 200 to 500 v. on cellulose acetate strips is reported. Experience in 166 determinations on 137 patients shows the method to be a simple, practical, and apparently sensitive one for the determination of FIGLU in the urine. Results of the application of the measurement of urinary FIGLU with histidine loading as a test for folic acid deficiency are also reported.

Entities: Chemical Disease Species

Keywords: ELECTROPHORESIS; FOLIC ACID/deficiency; GLUTAMATES/urine

Mesh：

Substances：

Year: 1961 PMID： 13757596 PMCID： PMC480232 DOI： 10.1136/jcp.14.4.345

Source DB: PubMed Journal: J Clin Pathol ISSN： 0021-9746 Impact factor: 3.411

13 in total

1. The clearance from the plasma of folic acid injected intravenously in normal subjects and patients with megaloblastic anaemia.

Authors: I CHANARIN; D L MOLLIN; B B ANDERSON
Journal: Br J Haematol Date: 1958-10 Impact factor: 6.998

2. A single-dose anthelmintic in general practice.

Authors: G KAGAN
Journal: Lancet Date: 1961-01-14 Impact factor: 79.321

3. Urinary excretion of formiminoglutamic acid: application in diagnosis of clinical folic acid deficiency.

Authors: A L Luhby; J M Cooperman; D N Teller
Journal: Am J Clin Nutr Date: 1959 Jul-Aug Impact factor: 7.045

4. The measurement of folic acid activity in serum: a diagnostic aid in the differentiation of the megaloblastic anemias.

Authors: V HERBERT; H BAKER; O FRANK; I PASHER; H SOBOTKA; L R WASSERMAN
Journal: Blood Date: 1960-02 Impact factor: 22.113

4. METABOLIC EFFECTS OF PARTIAL GASTRECTOMY WITH SPECIAL REFERENCE TO CALCIUM AND FOLIC ACID. II. THE CONTRIBUTION OF FOLIC ACID DEFICIENCY TO THE ANAEMIA.

Authors: D J DELLER; R N IBBOTSON; B CROMPTON
Journal: Gut Date: 1964-06 Impact factor: 23.059

Review 10. Drugs and folate metabolism.

Authors: D G Lambie; R H Johnson
Journal: Drugs Date: 1985-08 Impact factor: 9.546

Conventional voltage electrophoresis for formiminoglutamic-acid determination in folic acid deficiency.

1. The clearance from the plasma of folic acid injected intravenously in normal subjects and patients with megaloblastic anaemia.

2. A single-dose anthelmintic in general practice.

3. Urinary excretion of formiminoglutamic acid: application in diagnosis of clinical folic acid deficiency.

4. The measurement of folic acid activity in serum: a diagnostic aid in the differentiation of the megaloblastic anemias.

5. Urinary excretion of formiminoglutamic acid by human subjects after antifolic acid therapy.

6. A method for the determination of formiminoglutamic acid in urine.

7. Isolation of N-formyl-L-glutamic acid as an intermediate in the enzymatic degradation of L-histidine.

8. The enzymatic degradation of histidine.

9. Influence of succinylsulfathiazole and folic acid on glutamic acid excretion.

10. Studies on the folic acid activity of human serum.

1. FORMIMINO-GLUTAMIC ACID EXCRETION IN ANAEMIA OF PREGNANCY.

2. QUANTITATIVE ESTIMATION OF FORMIMINOGLUTAMIC ACID IN URINE.

3. STUDIES ON URINARY FORMIMINOGLUTAMIC ACID EXCRETION.

4. METABOLIC EFFECTS OF PARTIAL GASTRECTOMY WITH SPECIAL REFERENCE TO CALCIUM AND FOLIC ACID. II. THE CONTRIBUTION OF FOLIC ACID DEFICIENCY TO THE ANAEMIA.

5. FOLIC ACID DEFICIENCY IN HAEMOLYTIC ANAEMIA.

6. FOLIC-ACID DEFICIENCY IN RHEUMATOID ARTHRITIS.

7. FOLIC-ACID DEFICIENCY AND MEGALOBLASTIC ERYTHROPOIESIS IN MYELOFIBROSIS.

8. VALUE OF DETECTION OF FORMIMINOGLUTAMIC ACID IN URINE FOR THE DIAGNOSIS OF MALABSORPTION STATES.

9. PRACTICAL EVALUATION OF THE FIGLU TEST IN PREGNANCY WITH SPECIAL REFERENCE TO THE WHITE CELL CHANGES.

Review 10. Drugs and folate metabolism.