Literature DB >> 14245781

ABSENCE OF TASTE-BUD PAPILLAE IN FAMILIAL DYSAUTONOMIA.

A SMITH, A FARBMAN, J DANCIS.   

Abstract

No fungiform papillae could be found on the tongues of 30 patients with familial dysautonomia. In ten of these patients a search for vallate papillae was made, but none were found. Inspection of the tongue may thus be useful for diagnosing this rare disease, even in infants. Absence of these sensory receptors suggests that the multiple sensory deficits found in persons with familial dysautonomia may be related to defects in the peripheral receptors.

Entities:  

Keywords:  ABNORMALITIES; AUTONOMIC DYSFUNCTION; GENETICS, HUMAN; INFANT; TASTE BUDS

Mesh:

Substances:

Year:  1965        PMID: 14245781     DOI: 10.1126/science.147.3661.1040

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  15 in total

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Review 2.  A world without pain or tears.

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3.  Riley-Day syndrome: long-term ophthalmologic observations.

Authors:  S D Liebman
Journal:  Trans Am Ophthalmol Soc       Date:  1968

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Journal:  Physiol Behav       Date:  2006-06-19

5.  Localization of phosphatidylinositol signaling components in rat taste cells: role in bitter taste transduction.

Authors:  P M Hwang; A Verma; D S Bredt; S H Snyder
Journal:  Proc Natl Acad Sci U S A       Date:  1990-10       Impact factor: 11.205

Review 6.  The molecular basis of familial dysautonomia: overview, new discoveries and implications for directed therapies.

Authors:  Berish Y Rubin; Sylvia L Anderson
Journal:  Neuromolecular Med       Date:  2007-11-06       Impact factor: 3.843

7.  Genome-wide analysis of gene expression in primate taste buds reveals links to diverse processes.

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8.  Tocotrienol Treatment in Familial Dysautonomia: Open-Label Pilot Study.

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9.  IKAP expression levels modulate disease severity in a mouse model of familial dysautonomia.

Authors:  Paula Dietrich; Shanta Alli; Revathi Shanmugasundaram; Ioannis Dragatsis
Journal:  Hum Mol Genet       Date:  2012-08-24       Impact factor: 6.150

10.  Sensory and autonomic deficits in a new humanized mouse model of familial dysautonomia.

Authors:  Elisabetta Morini; Paula Dietrich; Monica Salani; Heather M Downs; Gregory R Wojtkiewicz; Shanta Alli; Anthony Brenner; Mats Nilbratt; John W LeClair; Anne Louise Oaklander; Susan A Slaugenhaupt; Ioannis Dragatsis
Journal:  Hum Mol Genet       Date:  2016-01-13       Impact factor: 6.150

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