Literature DB >> 14245778

CHOLESTEROL BIOSYNTHESIS: MEVALONATE SYNTHESIS INHIBITED BY BILE SALTS.

G M FIMOGNARI, V W RODWELL.   

Abstract

Certain bile salts inhibit biosynthesis of mevalonate from acetate-2-C(14) in normal rat liver homogenates. The physiological control of cholesterol biosynthesis is discussed.

Entities:  

Keywords:  BILE ACIDS AND SALTS; CHOLESTEROL; EXPERIMENTAL LAB STUDY; LIVER ENZYMOLOGY; LIVER FUNCTION; METABOLISM; MEVALONIC ACID; OXIDOREDUCTASES; PHARMACOLOGY; RATS; SOLUBILITY

Mesh：

Substances：

Year:  1965        PMID： 14245778     DOI： 10.1126/science.147.3661.1038

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  9 in total

Review 1.  Cholesterol metabolism in man.

Authors:  S M Grundy
Journal:  West J Med       Date:  1978-01

2.  An experimental basis for carcinogenic effects of ultraviolet radiation.

Authors:  H S Black
Journal:  Space Life Sci       Date:  1973-01

Review 3.  [Cholesterol metabolism].

Authors:  H J Weis
Journal:  Klin Wochenschr       Date:  1970-10-15

Review 4.  [Regulation of cholesterol synthesis].

Authors:  B Hamprecht
Journal:  Naturwissenschaften       Date:  1969-08

5.  Effect of dietary cholesterol and fasting on hepatic 3-hydroxy-3-methyl glutaryl coenzyme A hydrolase.

Authors:  M Saleemuddin; M Siddiqi
Journal:  Lipids       Date:  1972-09       Impact factor: 1.880

6.  Diet, cholesterol metabolism, and atherosclerosis.

Authors:  K K Carroll
Journal:  J Am Oil Chem Soc       Date:  1967-11       Impact factor: 1.849

7.  Mechanism of suckling-rat hypercholesteremia. II. Cholesterol biosynthesis and cholic acid turnover studies.

Authors:  R A Harris; E R Rivera; C L Villemez; F W Quackenbush
Journal:  Lipids       Date:  1967-03       Impact factor: 1.880

8.  Mechanisms of lithogenic bile formation in American Indian women with cholesterol gallstones.

Authors:  S M Grundy; A L Metzger; R D Adler
Journal:  J Clin Invest       Date:  1972-12       Impact factor: 14.808

9.  Comparison of the effects of cholic acid and chenic acid feeding on rates of cholesterol synthesis in the liver of the rat.

Authors:  M Carrella; J M Dietschy
Journal:  Am J Dig Dis       Date:  1977-04
  9 in total

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