Literature DB >> 14243759

THE CHEMICAL REACTIVITY OF THE THIOL GROUP IN THE ACTIVE CENTRE OF FICIN.

M R HOLLAWAY, A P MATHIAS, B R RABIN.   

Abstract

Entities:  

Keywords:  AMIDES; CHEMISTRY; ENZYME INHIBITORS; EXPERIMENTAL LAB STUDY; HYDROGEN-ION CONCENTRATION; KINETICS; PEPTIDE PEPTIDOHYDROLASES; SULFHYDRYL COMPOUNDS

Mesh：

Substances：

Year:  1964        PMID： 14243759     DOI： 10.1016/0926-6569(64)90275-5

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


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  12 in total

1.  The pH-dependence of second-order rate constants of enzyme modification may provide free-reactant pKa values.

Authors:  K Brocklehurst; H B Dixon
Journal:  Biochem J       Date:  1977-12-01       Impact factor: 3.857

2.  Study of the thermal denaturation of ribonuclease A by differential thermal analysis and susceptibility to proteolysis.

Authors:  B G Winchester; A P Mathias; B R Rabin
Journal:  Biochem J       Date:  1970-04       Impact factor: 3.857

3.  The preparation and properties of ficin chemically attached to carboxymethylcellulose.

Authors:  W E Hornby; M D Lilly; E M Crook
Journal:  Biochem J       Date:  1966-02       Impact factor: 3.857

4.  Preparation of fully active ficin from Ficus glabrata by covalent chromatography and characterization of its active centre by using 2,2'-depyridyl disulphide as a reactivity probe.

Authors:  J P Malthouse; K Brocklehurst
Journal:  Biochem J       Date:  1976-11       Impact factor: 3.857

5.  Evidence for a close similarity in the catalytic sites of papain and ficin in near-neutral media despite differences in acidic and alkaline media. Kinetics of the reactions of papain and ficin with chloroacetate.

Authors:  K Brocklehurst; S M Mushiri; G Patel; F Willenbrock
Journal:  Biochem J       Date:  1982-01-01       Impact factor: 3.857

6.  Ficin-Catalyzed Reactions. Hydrolysis of alpha-N-Benzoyl-l-Arginine Ethyl Ester and alpha-N-Benzoyl-l-Argininamide.

Authors:  D E Kramer; J R Whitaker
Journal:  Plant Physiol       Date:  1969-04       Impact factor: 8.340

7.  Evidence for histidine in the active sites of ficin and stem-bromelain.

Authors:  S S Husain; G Lowe
Journal:  Biochem J       Date:  1968-11       Impact factor: 3.857

8.  DIRECT EVIDENCE FOR AN ACYLATED THIOL AS AN INTERMEDIATE IN PAPAIN- AND FICIN-CATALYSED HYDROLYSES.

Authors:  G LOWE; A WILLIAMS
Journal:  Biochem J       Date:  1965-07       Impact factor: 3.857

9.  The amino acid sequence around the active-site cysteine and histidine residues, and the buried cysteine residue in ficin.

Authors:  S S Husain; G Lowe
Journal:  Biochem J       Date:  1970-04       Impact factor: 3.857

10.  The chemistry of xanthine oxidase. Reaction with iodoacetamide.

Authors:  R C Bray; D C Watts
Journal:  Biochem J       Date:  1966-01       Impact factor: 3.857
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