Literature DB >> 14217913

SEROLOGIC STRAIN DIFFERENTIATION IN TRACHOMA.

R L NICHOLS, D E MCCOMB.   

Abstract

An in vitro test for the differentiation of trachoma strain isolates was described. The method was based on absorption of trachoma antiserum followed by immunofluorescent staining of individual trachoma strains. Nineteen trachoma strains were studied; two main types were identified. Evidence for quantitative and qualitative antigenic variation between the two types was presented. The limitations in practice and in theory of the test were emphasized.

Entities:  

Keywords:  ABSORPTION; ANTIGENS; CHLAMYDIA; FLUORESCENT ANTIBODY TECHNIC; HEAT; IMMUNE SERUMS; TRACHOMA

Mesh：

Substances：

Year:  1964        PMID： 14217913      PMCID： PMC2137777          DOI： 10.1084/jem.120.4.639

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  11 in total

1.  CLASSIFICATION OF TRACHOMA VIRUS STRAINS BY PROTECTION OF MICE FROM TOXIC DEATH.

Authors:  S P WANG; J T GRAYSTON
Journal:  J Immunol       Date:  1963-06       Impact factor: 5.422

2.  Attempt to immunize a volunteer (with formalin-inactivated virus) against experimental trachoma induced by Saudi Arabian strain 2.

Authors:  J C SNYDER; S D BELL; E S MURRAY; P THYGESON; N HADDAD
Journal:  Ann N Y Acad Sci       Date:  1962-03-05       Impact factor: 5.691

3.  Differentiation of trachoma strains on the basis of immunization against toxic death of mice.

Authors:  S D BELL; B THEOBALD
Journal:  Ann N Y Acad Sci       Date:  1962-03-05       Impact factor: 5.691

4.  Antigenic relationshkps of trachoma virus strains in the mouse toxicity prevention test.

Authors:  I CHANG; S WANG; J T GRAYSTON
Journal:  Ann N Y Acad Sci       Date:  1962-03-05       Impact factor: 5.691

5.  The production of antisera that neutralize inclusion blennorrhoea virus.

Authors:  W A BLYTH; P REEVE; D M GRAHAM; J TAVERNE
Journal:  Br J Exp Pathol       Date:  1962-06

6.  Observations on the antigenic relationship between the virus of enzootic abortion in ewes and viruses of the psittacosis-lymphogranuloma group.

Authors:  K A MONSUR; C F BARWELL
Journal:  Br J Exp Pathol       Date:  1951-10

7.  The laboratory diagnosis of lymphogranuloma venereum.

Authors:  S P BEDSON; C F BARWELL
Journal:  J Clin Pathol       Date:  1949-11       Impact factor: 3.411

8.  Immunization of mice against toxic doses of homologous elementary bodies of trachoma.

Authors:  S D BELL; J C SNYDER; E S MURRAY
Journal:  Science       Date:  1959-09-11       Impact factor: 47.728

9.  Studies on trachoma. II. Comparison of fluorescent antibody, giemsa, and egg isolation methods for detection of trachoma virus in human conjunctival scrapings.

Authors:  R L NICHOLS; D E McCO MB; N HADDAD; E S MURRAY
Journal:  Am J Trop Med Hyg       Date:  1963-03       Impact factor: 2.345

10.  Strain-specific elements in influenza antigens.

Authors:  G K HIRST
Journal:  J Exp Med       Date:  1952-12       Impact factor: 14.307
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  8 in total

1.  Serotypes of trachoma agent isolated in the Gambia: with an observation on the relation between serotype and morphology.

Authors:  J Sowa; L H Collier; S Sowa
Journal:  J Hyg (Lond)       Date:  1974-06

2.  A comparison of the iodine and fluorescent antibody methods for staining trachoma inclusions in the conjunctiva.

Authors:  J Sowa; L H Collier; S Sowa
Journal:  J Hyg (Lond)       Date:  1971-12

3.  Immunogenicity of experimental trachoma vaccines in baboons. II. Experiments with adjuvants, and tests of cross-protection.

Authors:  L H Collier; W A Blyth
Journal:  J Hyg (Lond)       Date:  1966-12

4.  The present status of trachoma vaccination studies.

Authors:  L H Collier
Journal:  Bull World Health Organ       Date:  1966       Impact factor: 9.408

5.  Comparison of two panels of monoclonal antibodies for determination of Chlamydia trachomatis serovars.

Authors:  J M Ossewaarde; M Rieffe; A de Vries; R P Derksen-Nawrocki; H J Hooft; G J van Doornum; A M van Loon
Journal:  J Clin Microbiol       Date:  1994-12       Impact factor: 5.948

6.  Outbreak of non-specific urethritis associated with the presence of complement-fixing antibodies to the LB4 strain of TRIC agent.

Authors:  T Pasieczny; R G Sommerville
Journal:  Br J Vener Dis       Date:  1966-09

7.  Animal model studies of genital chlamydial infections. Immunity to re-infection with guinea-pig inclusion conjunctivitis agent in the urethra and eye of male guinea-pigs.

Authors:  L V Howard; M P O'Leary; R L Nichols
Journal:  Br J Vener Dis       Date:  1976-08

8.  Antibody type specificity to trachoma in eye secretions of saudi arab children.

Authors:  D E McComb; R L Nichols
Journal:  Infect Immun       Date:  1970-07       Impact factor: 3.441
  8 in total

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