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Literature DB >> 13798522

Immunization of mice against toxic doses of homologous elementary bodies of trachoma.

Abstract

Death of mice occurs 2 to 8 hours after intravenous inoculation of concentrated viable elementary bodies of trachoma. Toxic death can be prevented by vaccinating the mice with concentrated suspensions of homologous strains inactivated by formalin or phenol. Judged by toxic challenges, at least two antigenically distinct types of elementary bodies of trachoma occur in Saudi Arabia and Egypt.

Entities: Chemical Disease Species

Keywords: TRACHOMA/immunology

Mesh：

Year: 1959 PMID： 13798522 DOI： 10.1126/science.130.3376.626

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

16 in total

1. Observatios on the growth of trachoma and inclusion blennorrhoea viruses in embryonate eggs.

Authors: P REEVE; J TAVERNE
Journal: J Hyg (Lond) Date: 1963-03

2. FEELING the COLD.

Authors:
Journal: Br Med J Date: 1959-11-14

3. The serum and conjunctival antibody response to trachoma in Gambian children.

Authors: L H Collier; J Sowa; S Sowa
Journal: J Hyg (Lond) Date: 1972-12

4. Immunological classification of TRIC agents and of some recently isolated LGV agents by the micro-immunofluorescence test.

Authors: J D Treharne; S J Davey; S J Gray; B R Jones
Journal: Br J Vener Dis Date: 1972-02

5. Acute bacterial conjunctivitis in Assiout, Upper Egypt. A one-year study.

Authors: L S Nakhla; M K al-Hussaini; A A Shokeir
Journal: Br J Ophthalmol Date: 1970-08 Impact factor: 4.638

6. Serotypes of trachoma agent isolated in the Gambia: with an observation on the relation between serotype and morphology.

Authors: J Sowa; L H Collier; S Sowa
Journal: J Hyg (Lond) Date: 1974-06

Immunization of mice against toxic doses of homologous elementary bodies of trachoma.

1. Observatios on the growth of trachoma and inclusion blennorrhoea viruses in embryonate eggs.

2. FEELING the COLD.

3. The serum and conjunctival antibody response to trachoma in Gambian children.

4. Immunological classification of TRIC agents and of some recently isolated LGV agents by the micro-immunofluorescence test.

5. Acute bacterial conjunctivitis in Assiout, Upper Egypt. A one-year study.

6. Serotypes of trachoma agent isolated in the Gambia: with an observation on the relation between serotype and morphology.

7. Comparison of two panels of monoclonal antibodies for determination of Chlamydia trachomatis serovars.

8. Immediate cytotoxicity of Chlamydia trachomatis for mouse peritoneal macrophages.

9. Rapid immunotyping of Chlamydia trachomatis with monoclonal antibodies in a solid-phase enzyme immunoassay.

10. Identification and properties of chlamydial polypeptides that bind eucaryotic cell surface components.