Literature DB >> 14207459

ACTINOMYCIN D: AN EFFECT ON RAT LIVER HOMOGENATES UNRELATED TO ITS ACTION ON RNA SYNTHESIS.

M REVEL, H H HIATT, J P REVEL.   

Abstract

Liver homogenates prepared from rats injected with high doses of actinomycin D show a decrease in polyribosome content and in amino acid incorporation. These effects are not observed in rat liver not subjected to homogenization and are independent of the inhibition of RNA synthesis caused by the antibiotic.

Entities:  

Keywords:  ACTINOMYCIN; AMINO ACID METABOLISM; EXPERIMENTAL LAB STUDY; HOMOGENATES; LIVER CYTOLOGY; METABOLISM; MICROSOMES; PATHOLOGY; PHARMACOLOGY; RATS; RIBOSOMES; RNA

Mesh：

Substances：

Year:  1964        PMID： 14207459     DOI： 10.1126/science.146.3649.1311

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  32 in total

1.  Induction of tyrosine alpha-ketoglutarate transaminase by steroid hormones in a newly established tissue culture cell line.

Authors:  E B Thompson; G M Tomkins; J F Curran
Journal:  Proc Natl Acad Sci U S A       Date:  1966-07       Impact factor: 11.205

2.  Stability of cytoplasmic messenger RNA in HeLa cels.

Authors:  W Murphy; G Attardi
Journal:  Proc Natl Acad Sci U S A       Date:  1973-01       Impact factor: 11.205

3.  Studies on Phytoalexins: The Relationship between Actinomycin D and Ribonucleic Acid Synthesis during the Induction of Phaseollin in the French Bean (Phaseolus vulgaris L.).

Authors:  D R Biggs
Journal:  Plant Physiol       Date:  1972-12       Impact factor: 8.340

4.  Evidence for an Inactivating System of Nitrate Reductase in Hordeum vulgare L. during Darkness That Requires Protein Synthesis.

Authors:  R L Travis; W R Jordan; R C Huffaker
Journal:  Plant Physiol       Date:  1969-08       Impact factor: 8.340

5.  Evidence for in vivo Light-induced Synthesis of Ribulose-1,5-diP Carboxylase and Phosphoribulokinase in Greening Barley Leaves.

Authors:  C J Keller; R C Huffaker
Journal:  Plant Physiol       Date:  1967-09       Impact factor: 8.340

6.  Inhibition of replication of lactic dehydrogenase virus by actinomycin.

Authors:  S Yamazaki; A L Notkins
Journal:  J Virol       Date:  1973-04       Impact factor: 5.103

7.  Inhibition by actinomycin D of uridine diphosphoglucose synthetase activity during differentiation of Dictyostelium discoideum.

Authors:  B Wright; R Pannbacker
Journal:  J Bacteriol       Date:  1967-06       Impact factor: 3.490

8.  Regulation of polyribosome formation and protein synthesis in the uterus. Effect of administration of graded doses of oestradiol-17-beta and actinomycin D on the amino acid-incorporation activity in vitro and the cytoplasmic concentration in vivo of polyribosomes.

Authors:  C S Teng; T H Hamilton
Journal:  Biochem J       Date:  1970-07       Impact factor: 3.857

9.  Differential inhibitory effects of actinomycin D among strains of poliovirus.

Authors:  F L Schaffer; M Gordon
Journal:  J Bacteriol       Date:  1966-06       Impact factor: 3.490

10.  Ribonucleic acid synthesis in porphyric rat liver induced by 3,5-dicarbethoxy-1,4-dihydrocollidine.

Authors:  H Nawata; K Kato
Journal:  Biochem J       Date:  1973-09       Impact factor: 3.857
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.