| Literature DB >> 14197560 |
H SIDRANSKY, T STAEHELIN, E VERNEY.
Abstract
There is enhanced incorporation of leucine-C(14) into proteins in cell-free preparations from livers of young rats force-fed a threonine-devoid diet for 3 days. This increased protein synthesis in the liver is related predominantly to enhanced activity of ribosomes. The aggregates of liver ribosomes (ergosonmes or polysomes) as measured in a sucrose gradient indicated a shift from lighter toward heavier ergosomes with a decrease in monomers.Entities:
Keywords: AMINO ACID METABOLISM; CARBON ISOTOPES; DEFICIENCY DISEASES; EXPERIMENTAL LAB STUDY; LEUCINE; LIVER FUNCTION; PROTEIN METABOLISM; RIBOSOMES; THREONINE
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Year: 1964 PMID： 14197560 DOI： 10.1126/science.146.3645.766
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728