Literature DB >> 1418730

Construction of cancer vaccines with carbohydrate and protein (peptide) tumor antigens.

P O Livingston1.   

Abstract

Tumor vaccinology is as old as immunological thought and as young as our rapidly evolving understanding of antigen processing and presentation. The recent availability of carbohydrate and peptide tumor antigens suitable for vaccine construction, conjugate and recombinant vector technologies capable of augmenting helper and cytotoxic T cell activity and potent new immunological adjuvants have combined to produce considerable optimism for the future of tumor vaccines.

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Year:  1992        PMID: 1418730     DOI: 10.1016/0952-7915(92)90038-g

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN: 0952-7915            Impact factor:   7.486


  11 in total

1.  Synthesis of double C-glycoside analogue of sTn.

Authors:  Dino K Ress; Sultan N Baytas; Qun Wang; Eva M Muñoz; Kazuo Tokuzoki; Hiroshi Tomiyama; Robert J Linhardt
Journal:  J Org Chem       Date:  2005-09-30       Impact factor: 4.354

Review 2.  Biosynthesis and functions of gangliosides: recent advances.

Authors:  K O Lloyd; K Furukawa
Journal:  Glycoconj J       Date:  1998-07       Impact factor: 2.916

3.  Characterization of a mouse monoclonal IgG3 antibody to the tumor-associated globo H structure produced by immunization with a synthetic glycoconjugate.

Authors:  V Kudryashov; G Ragupathi; I J Kim; M E Breimer; S J Danishefsky; P O Livingston; K O Lloyd
Journal:  Glycoconj J       Date:  1998-03       Impact factor: 2.916

Review 4.  Peptide mimotopes of carbohydrate antigens.

Authors:  T Kieber-Emmons
Journal:  Immunol Res       Date:  1998       Impact factor: 2.829

5.  Synthesis and immunological properties of N-modified GM3 antigens as therapeutic cancer vaccines.

Authors:  Yanbin Pan; Peter Chefalo; Nancy Nagy; Clifford Harding; Zhongwu Guo
Journal:  J Med Chem       Date:  2005-02-10       Impact factor: 7.446

6.  Allylmalonamide as a bivalent linker: synthesis of biantennary GM3-saccharide--keyhole limpet hemocyanin glycoconjugate and the immune response in mice.

Authors:  W Zou; M Abraham; M Gilbert; W W Wakarchuk; H J Jennings
Journal:  Glycoconj J       Date:  1999-09       Impact factor: 2.916

Review 7.  Potential role of granulocyte-macrophage colony-stimulating factor as vaccine adjuvant.

Authors:  T Jones; A Stern; R Lin
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1994       Impact factor: 3.267

8.  Efficient metabolic engineering of GM3 on tumor cells by N-phenylacetyl-D-mannosamine.

Authors:  Peter Chefalo; Yanbin Pan; Nancy Nagy; Zhongwu Guo; Clifford V Harding
Journal:  Biochemistry       Date:  2006-03-21       Impact factor: 3.162

9.  Efficient glycoengineering of GM3 on melanoma cell and monoclonal antibody-mediated selective killing of the glycoengineered cancer cell.

Authors:  Qianli Wang; Junping Zhang; Zhongwu Guo
Journal:  Bioorg Med Chem       Date:  2007-09-12       Impact factor: 3.641

10.  Accessibility of N-acyl-D-mannosamines to N-acetyl-D-neuraminic acid aldolase.

Authors:  Yanbin Pan; Tiffany Ayani; Janos Nadas; Shouming Wen; Zhongwu Guo
Journal:  Carbohydr Res       Date:  2004-08-23       Impact factor: 2.104

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