| Literature DB >> 14186465 |
K ONOUE, Y YAGI, P STELOS, D PRESSMAN.
Abstract
Direct evidence is provided for the antigen binding activity of the 6S subunits formed by reduction and alkylation of rabbit beta2-macroglobulin antibody. Binding activity of the subunits was clearly demonstrated by radioimmunoelectrophoresis with a preparation of purified rabbit antibody against the p-azobenzenearsonate group, which contained 40 percent of beta2M-antibody. The precipitate arc formed between the subunits and sheep antiserum against rabbit macroglobulin was shown to bind radioactive antigen specifically.Entities:
Keywords: ANTIGEN-ANTIBODY REACTIONS; EXPERIMENTAL LAB STUDY; IMMUNOELECTROPHORESIS; MACROGLOBULINS
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Year: 1964 PMID： 14186465 DOI： 10.1126/science.146.3642.404
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728