Literature DB >> 14163814

ELECTRON MICROSCOPIC AND BIOCHEMICAL STUDIES OF PYRUVATE DEHYDROGENASE COMPLEX OF ESCHERICHIA COLI.

L J REED, H FERNANDEZ-MORAN, M KOIKE, C R WILLMS.   

Abstract

Examination with the electron microscope of the pyruvate dehydrogenase complex and its component enzymes from Escherichia coli indicates that the complex has a polyhedral structure with a diameter of about 300 to 350 angstroms and a height of 200 to 250 angstroms. The reconstituted complex closely resembles the native complex in appearance. A tentative model of this multienzyme complex is proposed on the basis of the correlated biochemical and electron-microscopic data

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Keywords:  ACETATES; ACYLTRANSFERASES; CARBOXY-LYASES; ESCHERICHIA COLI; EXPERIMENTAL LAB STUDY; LIPOIC ACID; MICROSCOPY, ELECTRON; OXIDOREDUCTASES; PHOSPHOTUNGSTIC ACID; PYRUVATES; STAINS AND STAINING

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Year:  1964        PMID: 14163814     DOI: 10.1126/science.145.3635.930

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  8 in total

1.  From lipoic acid to multi-enzyme complexes.

Authors:  L J Reed
Journal:  Protein Sci       Date:  1998-01       Impact factor: 6.725

2.  Alpha-Keto acid dehydrogenase complexes, V. Macromolecular organization of pyruvate and alpha-ketoglutarate dehydrogenase complexes isolated from beef kidney mitochondria.

Authors:  E Ishikawa; R M Oliver; L J Reed
Journal:  Proc Natl Acad Sci U S A       Date:  1966-08       Impact factor: 11.205

3.  Uncovering the beginning of diabetes: the cellular redox status and oxidative stress as starting players in hyperglycemic damage.

Authors:  João Soeiro Teodoro; Ana Patrícia Gomes; Ana Teresa Varela; Filipe Valente Duarte; Anabela Pinto Rolo; Carlos Marques Palmeira
Journal:  Mol Cell Biochem       Date:  2013-01-08       Impact factor: 3.396

4.  Supramolecular organization of enzyme and membrane systems.

Authors:  A L Lehninger
Journal:  Naturwissenschaften       Date:  1966-02

5.  Actinobacteria challenge the paradigm: A unique protein architecture for a well-known, central metabolic complex.

Authors:  Eduardo M Bruch; Pierre Vilela; Lu Yang; Alexandra Boyko; Norik Lexa-Sapart; Bertrand Raynal; Pedro M Alzari; Marco Bellinzoni
Journal:  Proc Natl Acad Sci U S A       Date:  2021-11-30       Impact factor: 11.205

6.  Molecular structure of the pyruvate dehydrogenase complex from Escherichia coli K-12.

Authors:  O Vogel; B Hoehn; U Henning
Journal:  Proc Natl Acad Sci U S A       Date:  1972-06       Impact factor: 11.205

7.  X-ray small-angle studies of the pyruvate dehydrogenase core complex from Escherichia coli K-12. II. Subunit structure of the core complex.

Authors:  H Durchschlag
Journal:  Biophys Struct Mech       Date:  1975-05-30

8.  Citrate cycle and related metabolism of Listeria monocytogenes.

Authors:  T L Trivett; E A Meyer
Journal:  J Bacteriol       Date:  1971-09       Impact factor: 3.490

  8 in total

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