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Literature DB >> 14082360

ROLE OF SERINE IN CHYMOTRYPSIN ACTION. CONVERSION OF THE ACTIVE SERINE TO DEHYDROALANINE.

D H STRUMEYER, W N WHITE, D E KOSHLAND.

Abstract

Entities: Chemical Disease

Keywords: ALANINE; CHYMOTRYPSIN; EXPERIMENTAL LAB STUDY; PROTEIN METABOLISM; SERINE

Mesh：

Substances：

Year: 1963 PMID： 14082360 PMCID： PMC221950 DOI： 10.1073/pnas.50.5.931

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

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7 in total

1. The kinetics of enzyme-catalyzed reactions with two or more substrates or products. I. Nomenclature and rate equations.

Authors: W W CLELAND
Journal: Biochim Biophys Acta Date: 1963-01-08

2. Amino acids involved in the action of chymotrypsin.

Authors: D E KOSHLAND; D H STRUMEYER; W J RAY
Journal: Brookhaven Symp Biol Date: 1962-12

3. Phosphate incorporation into alkaline phosphatase of E. coli.

Authors: J H SCHWARTZ; F LIPMANN
Journal: Proc Natl Acad Sci U S A Date: 1961-12-15 Impact factor: 11.205

4. Chemical nature of the DFP-binding site of pseudocholinesterase.

Authors: H S JANSZ; D BRONS; M G WARRINGA
Journal: Biochim Biophys Acta Date: 1959-08

5. Properties of the phosphorylated active site of phosphoglucomutase.

Authors: E P KENNEDY; D E KOSHLAND
Journal: J Biol Chem Date: 1957-09 Impact factor: 5.157

6. A study of the linkage of phosphorus to protein in phosphoglucomutase.

Authors: L ANDERSON; G R JOLLES
Journal: Arch Biochem Biophys Date: 1957-07 Impact factor: 4.013

7. Stoichiometric inhibition of chymotrypsin.

Authors: A K BALLS; E F JANSEN
Journal: Adv Enzymol Relat Subj Biochem Date: 1952

7 in total

15 in total

1. AN ISOMORPHOUS HEAVY ATOM SUBSTITUTION AT THE ACTIVE SITE OF GAMMA-CHYMOTRYPSIN.

Authors: P B SIGLER; H C SKINNER; C L COULTER; J KALLOS; H BRAXTON; D R DAVIES
Journal: Proc Natl Acad Sci U S A Date: 1964-06 Impact factor: 11.205

2. Egg-white and blood-serum proteins functioning by noncovalent interactions: studies by chemical modification and comparative biochemistry.

Authors: R E Feeney; D T Osuga
Journal: J Protein Chem Date: 1988-12

3. The conversion of serine at the active site of subtilisin to cysteine: a "chemical mutation".

Authors: K E Neet; D E Koshland
Journal: Proc Natl Acad Sci U S A Date: 1966-11 Impact factor: 11.205

4. A systematic method for introducing heavy atoms into a protein molecule.

Authors: A Fenselau; D Koenig; D E Koshland; H G Latham; H Weiner
Journal: Proc Natl Acad Sci U S A Date: 1967-06 Impact factor: 11.205

5. The mechanism of action of aldolases. XI. Activation by aromatic sulfhydryl reagents and beta-elimination of selected thiol groups.

Authors: T Cremona; J Kowal; B L Horecker
Journal: Proc Natl Acad Sci U S A Date: 1965-06 Impact factor: 11.205