| Literature DB >> 14075695 |
A RICH, S PENMAN, Y BECKER, J DARNELL, C HALL.
Abstract
HeLa cells normally contain a distribution of polysome sizes, and the largest polysomes contain over 40 ribosomes. After infection with polio virus and actinomycin-D treatment, a new class of polio-induced polysomes are found, some of which contain up to 60 ribosomes. Examinaton of these polysomes suggests a mechanism for protein synthesis with this polycistronic RNA.Entities:
Keywords: EXPERIMENTAL LAB STUDY; NUCLEOPROTEINS; POLIOVIRUS; PROTEIN METABOLISM; RNA; RNA, VIRAL; TISSUE CULTURE
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Substances:
Year: 1963 PMID: 14075695 DOI: 10.1126/science.142.3600.1658
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728