Literature DB >> 14069549

STUDIES OF FLUORINATED PYRIMIDINES. XVIII. THE DEGRADATION OF 5-FLUORO-2'-DEOXYURIDINE AND RELATED COMPOUNDS BY NUCLEOSIDE PHOSPHORYLASE.

G D BIRNIE, H KROEGER, C HEIDELBERGER.   

Abstract

Entities:  

Keywords:  CARCINOMA, EHRLICH TUMOR; EXPERIMENTAL LAB STUDY; FLUORODEOXYURIDINE; GLUCOSYLTRANSFERASES; METABOLISM; MICE

Mesh：

Substances：

Year:  1963        PMID： 14069549     DOI： 10.1021/bi00903a031

Source DB:  PubMed          Journal:  Biochemistry        ISSN： 0006-2960            Impact factor:   3.162


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  22 in total

1.  Modification of uridine phosphorylase from Escherichia coli by diethyl pyrocarbonate. Evidence for a histidine residue in the active site of the enzyme.

Authors:  A K Drabikowska; G Woźniak
Journal:  Biochem J       Date:  1990-09-01       Impact factor: 3.857

2.  Clinical trial of intrathecal administration of 5-fluoro-2'-deoxyuridine for treatment of meningeal dissemination of malignant tumors.

Authors:  H Nakagawa; M Yamada; N Maeda; K Iwatsuki; A Hirayama; K Ikenaka
Journal:  J Neurooncol       Date:  1999       Impact factor: 4.130

3.  Effects of 5-fluoro-2'-deoxyuridine on bacterial growth. Its use for DNA labelling.

Authors:  T Reuvers; D García-Pineda; C A Dávila
Journal:  Antonie Van Leeuwenhoek       Date:  1973       Impact factor: 2.271

4.  Floxuridine amino acid ester prodrugs: enhancing Caco-2 permeability and resistance to glycosidic bond metabolism.

Authors:  Christopher P Landowski; Xueqin Song; Philip L Lorenzi; John M Hilfinger; Gordon L Amidon
Journal:  Pharm Res       Date:  2005-08-24       Impact factor: 4.200

5.  Phosphorolysis of 5-fluoro-2'-deoxyuridine in Escherichia coli and its inhibition by nucleosides.

Authors:  E Yagil; A Rosner
Journal:  J Bacteriol       Date:  1971-11       Impact factor: 3.490

6.  The development of orally administrable gemcitabine prodrugs with D-enantiomer amino acids: enhanced membrane permeability and enzymatic stability.

Authors:  Yasuhiro Tsume; Tuba Incecayir; Xueqin Song; John M Hilfinger; Gordon L Amidon
Journal:  Eur J Pharm Biopharm       Date:  2013-12-19       Impact factor: 5.571

7.  The utilization of some halogenated aromatic acids by Nocardia. Effects on growth and enzyme induction.

Authors:  A Smith; E K Tranter; R B Cain
Journal:  Biochem J       Date:  1968-01       Impact factor: 3.857

8.  Gene regulation and functional alterations induced by Kaposi's sarcoma-associated herpesvirus-encoded ORFK13/vFLIP in endothelial cells.

Authors:  Shuhei Sakakibara; Cynthia A Pise-Masison; John N Brady; Giovanna Tosato
Journal:  J Virol       Date:  2008-12-17       Impact factor: 5.103

9.  Effect of guanosine on antitumor activity of fluorinated pyrimidines against P 388 leukemia.

Authors:  M Iigo; A Hoshi
Journal:  Cancer Chemother Pharmacol       Date:  1984       Impact factor: 3.333

10.  Enhanced cancer cell growth inhibition by dipeptide prodrugs of floxuridine: increased transporter affinity and metabolic stability.

Authors:  Yasuhiro Tsume; John M Hilfinger; Gordon L Amidon
Journal:  Mol Pharm       Date:  2008-07-25       Impact factor: 4.939
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