| Literature DB >> 14047631 |
Abstract
Alpha-methyldopa in amounts of 750 mg twice daily is an effective antihypertensive agent, intermediate in potency between reserpine-thiazide combinations and ganglionic-sympathetic blocking drugs. Because it produces few undesirable side effects, it is well accepted by patients.It is useful for patients with moderate or severe hypertension not controlled by reserpine-thiazide combinations. Its favorable action on cardiac output and renal blood flow provides special advantages for patients with advanced hypertension aggravated by cardiac or renal combinations.Entities:
Keywords: ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE DETERMINATION; HYPERTENSION; KIDNEY FUNCTION TESTS; METABOLISM; METHYLDOPA; SODIUM; TOXICOLOGIC REPORT
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Year: 1963 PMID: 14047631 PMCID: PMC1515254
Source DB: PubMed Journal: Calif Med ISSN: 0008-1264