Literature DB >> 14047211

ANTAGONISM OF D-CYCLOSERINE INHIBITION OF MYCOBACTERIAL GROWTH BY D-ALANINE.

W A ZYGMUNT.   

Abstract

Zygmunt, Walter A. (Mead Johnson & Co., Evansville, Ind.). Antagonism of d-cycloserine inhibition of mycobacterial growth by d-alanine. J. Bacteriol. 85:1217-1220. 1963.-Reversal of the antimycobacterial activity of d-4-amino-3-isoxazolidinone (d-cycloserine) by alanine in two species of mycobacteria actively growing on chemically defined media was compared. In both instances, d-alanine was the most effective reversal agent. The specificity with which the d isomer reversed the antimycobacterial activity of d-cycloserine was more pronounced than that observed with other species of bacteria. Mycobactin, a growth factor for certain mycobacteria, showed no reversal activity.

Entities:  

Keywords:  ALANINE; CYCLOSERINE; EXPERIMENTAL LAB STUDY; MYCOBACTERIUM

Mesh:

Substances:

Year:  1963        PMID: 14047211      PMCID: PMC278322          DOI: 10.1128/jb.85.6.1217-1220.1963

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  6 in total

1.  A cell-wall mucopeptide complex obtained from the culture filtrate of tubercle bacilli.

Authors:  K TAKEYA; K HISATSUNE; K NAKASHIMA
Journal:  Biochim Biophys Acta       Date:  1961-12-23

2.  Reversal of cycloserine inhibition by D-alanine.

Authors:  G D SHOCKMAN
Journal:  Proc Soc Exp Biol Med       Date:  1959 Aug-Sep

3.  Studies on the cell-wall composition and taxonomy of Actinomycetales and related groups.

Authors:  C S CUMMINS; H HARRIS
Journal:  J Gen Microbiol       Date:  1958-02

4.  Inhibition of anitbacterial activity of cycloserine by alpha-alanine.

Authors:  A BONDI; J KORNBLUM; C FORTE
Journal:  Proc Soc Exp Biol Med       Date:  1957-10

5.  REVERSAL OF d-CYCLOSERINE INHIBITION OF BACTERIAL GROWTH BY ALANINE.

Authors:  W A Zygmunt
Journal:  J Bacteriol       Date:  1962-07       Impact factor: 3.490

6.  Occurrence of D-phenylalanine, D-allothreonine and other D-amino-acids in peptido-lipids of bacterial origin.

Authors:  M IKAWA; E E SNELL; E LEDERER
Journal:  Nature       Date:  1960-11-12       Impact factor: 49.962

  6 in total
  8 in total

1.  Mycobacterium smegmatis D-Alanine Racemase Mutants Are Not Dependent on D-Alanine for Growth.

Authors:  Ofelia Chacon; Zhengyu Feng; N Beth Harris; Nancy E Cáceres; L Garry Adams; Raúl G Barletta
Journal:  Antimicrob Agents Chemother       Date:  2002-01       Impact factor: 5.191

Review 2.  Intermediary metabolism of mycobacteria.

Authors:  T Ramakrishnan; P S Murthy; K P Gopinathan
Journal:  Bacteriol Rev       Date:  1972-03

Review 3.  Mycobactins: iron-chelating growth factors from mycobacteria.

Authors:  G A Snow
Journal:  Bacteriol Rev       Date:  1970-06

4.  Overexpression of the D-alanine racemase gene confers resistance to D-cycloserine in Mycobacterium smegmatis.

Authors:  N E Cáceres; N B Harris; J F Wellehan; Z Feng; V Kapur; R G Barletta
Journal:  J Bacteriol       Date:  1997-08       Impact factor: 3.490

5.  Kinetic and genetic analyses of D-cycloserine inhibition and resistance in Escherichia coli.

Authors:  R Curtiss; L J Charamella; C M Berg; P E Harris
Journal:  J Bacteriol       Date:  1965-11       Impact factor: 3.490

6.  Roles of Mycobacterium smegmatis D-alanine:D-alanine ligase and D-alanine racemase in the mechanisms of action of and resistance to the peptidoglycan inhibitor D-cycloserine.

Authors:  Zhengyu Feng; Raúl G Barletta
Journal:  Antimicrob Agents Chemother       Date:  2003-01       Impact factor: 5.191

7.  CIRCUMVENTION OF THE MYCOBACTIN REQUIREMENT OF MYCOBACTERIUM PARATUBERCULOSIS.

Authors:  N E MORRISON
Journal:  J Bacteriol       Date:  1965-03       Impact factor: 3.490

8.  Metabolomics analysis identifies d-Alanine-d-Alanine ligase as the primary lethal target of d-Cycloserine in mycobacteria.

Authors:  Steven Halouska; Robert J Fenton; Denise K Zinniel; Darrell D Marshall; Raúl G Barletta; Robert Powers
Journal:  J Proteome Res       Date:  2013-12-13       Impact factor: 4.466

  8 in total

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