| Literature DB >> 14047211 |
Abstract
Zygmunt, Walter A. (Mead Johnson & Co., Evansville, Ind.). Antagonism of d-cycloserine inhibition of mycobacterial growth by d-alanine. J. Bacteriol. 85:1217-1220. 1963.-Reversal of the antimycobacterial activity of d-4-amino-3-isoxazolidinone (d-cycloserine) by alanine in two species of mycobacteria actively growing on chemically defined media was compared. In both instances, d-alanine was the most effective reversal agent. The specificity with which the d isomer reversed the antimycobacterial activity of d-cycloserine was more pronounced than that observed with other species of bacteria. Mycobactin, a growth factor for certain mycobacteria, showed no reversal activity.Entities:
Keywords: ALANINE; CYCLOSERINE; EXPERIMENTAL LAB STUDY; MYCOBACTERIUM
Mesh:
Substances:
Year: 1963 PMID: 14047211 PMCID: PMC278322 DOI: 10.1128/jb.85.6.1217-1220.1963
Source DB: PubMed Journal: J Bacteriol ISSN: 0021-9193 Impact factor: 3.490