Literature DB >> 1401966

Immunological properties of ribosome-inactivating proteins and a saporin immunotoxin.

P Strocchi1, L Barbieri, F Stirpe.   

Abstract

Antibodies have been raised in rabbits against plant ribosome-inactivating proteins (RIPs) and used to demonstrate cross-reactivity between RIPs from plants belonging to the same family, but little or no cross-reactivity between RIPs from taxonomically unrelated plants. When an immunotoxin consisting of saporin conjugated to bovine IgG was injected into rabbits, the animals formed antibodies against both saporin and bovine IgG.

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Year:  1992        PMID: 1401966     DOI: 10.1016/0022-1759(92)90271-t

Source DB:  PubMed          Journal:  J Immunol Methods        ISSN: 0022-1759            Impact factor:   2.303


  5 in total

1.  Immunoconjugates made of an anti-EGF receptor monoclonal antibody and type 1 ribosome-inactivating proteins from Saponaria ocymoides or Vaccaria pyramidata.

Authors:  A M Di Massimo; M Di Loreto; A Pacilli; G Raucci; L D'Alatri; A Mele; A Bolognesi; L Polito; F Stirpe; R De Santis
Journal:  Br J Cancer       Date:  1997       Impact factor: 7.640

2.  Targeted dianthin is a powerful toxin to treat pancreatic carcinoma when applied in combination with the glycosylated triterpene SO1861.

Authors:  Cheenu Bhargava; Horst Dürkop; Xiangli Zhao; Alexander Weng; Matthias F Melzig; Hendrik Fuchs
Journal:  Mol Oncol       Date:  2017-09-15       Impact factor: 6.603

Review 3.  Dianthin and Its Potential in Targeted Tumor Therapies.

Authors:  Hendrik Fuchs
Journal:  Toxins (Basel)       Date:  2019-10-11       Impact factor: 4.546

4.  Kirkiin: A New Toxic Type 2 Ribosome-Inactivating Protein from the Caudex of Adenia kirkii.

Authors:  Massimo Bortolotti; Stefania Maiello; José M Ferreras; Rosario Iglesias; Letizia Polito; Andrea Bolognesi
Journal:  Toxins (Basel)       Date:  2021-01-22       Impact factor: 4.546

5.  An unusual type I ribosome-inactivating protein from Agrostemma githago L.

Authors:  Christoph Weise; Achim Schrot; Leonie T D Wuerger; Jacob Adolf; Roger Gilabert-Oriol; Simko Sama; Matthias F Melzig; Alexander Weng
Journal:  Sci Rep       Date:  2020-09-21       Impact factor: 4.379

  5 in total

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