| Literature DB >> 1398116 |
Abstract
We have isolated the cDNA and corresponding genomic DNA for the ilv-2 locus of Neurospora crassa. This gene encodes alpha-keto-beta-hydroxylacyl reductoisomerase (Ilv-2), required for the synthesis of isoleucine and valine. The gene contains four introns, maps to the right arm of chromosome V, and encodes a protein of 400 amino acids (aa). Alignment of the aa sequence of Ilv-2 with the two other known eukaryotic sequences encoding this enzyme reveals two conserved regions.Entities:
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Year: 1992 PMID: 1398116 DOI: 10.1016/0378-1119(92)90018-k
Source DB: PubMed Journal: Gene ISSN: 0378-1119 Impact factor: 3.688