Literature DB >> 13947582

Origin and biologic individuality of the genetic dictionary.

D GIACOMONI, S SPIEGELMAN.   

Abstract

Deoxyribonucleic acid contains sequences complementary to homologous amino-acid transfer ribonucleic acid molecules which serve as the translating device between polyribonucleotides and proteins. This implies that the RNA molecules have their primary origin in DNA. From the amount of DNA participating, one would infer that more than 20 complementary sequences exist per genome, a conclusion consistent with a degenerate code. The fact that complex formation occurs most readily with homologous RNA suggests that, while the language remains universal, each dictionary is uniquely identifiable with its own genome.

Keywords:  DNA, BACTERIAL; ESCHERICHIA COLI; RNA

Mesh:

Substances:

Year:  1962        PMID: 13947582     DOI: 10.1126/science.138.3547.1328

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  22 in total

1.  SELECTIVE INHIBITION OF SYNTHESIS OF RIBOSOMAL RNA IN ESCHERICHIA COLI BY LEVORPHANOL.

Authors:  E J SIMON; D VANPRAAG
Journal:  Proc Natl Acad Sci U S A       Date:  1964-06       Impact factor: 11.205

2.  USE OF THERMAL DENATURATION STUDIES TO INVESTIGATE THE BASE SEQUENCE OF YEAST SERINE SRNA.

Authors:  G FELSENFELD; G L CANTONI
Journal:  Proc Natl Acad Sci U S A       Date:  1964-05       Impact factor: 11.205

3.  AN RNA "REPLICASE" INDUCED BY AND SELECTIVE FOR A VIRAL RNA: ISOLATION AND PROPERTIES.

Authors:  I HARUNA; K NOZU; Y OHTAKA; S SPIEGELMAN
Journal:  Proc Natl Acad Sci U S A       Date:  1963-11       Impact factor: 11.205

4.  TRANSFER OF THE METHYL GROUP OF METHIONINE TO NUCLEOLAR RIBONUCLEIC ACID.

Authors:  J L SIRLIN; J JACOB; C J TANDLER
Journal:  Biochem J       Date:  1963-12       Impact factor: 3.857

5.  THE EFFECTS OF INHIBITORS OF MACROMOLECULAR BIOSYNTHESIS UPON THE PERSISTENT RHYTHM OF LUMINESCENCE IN GONYAULAX.

Authors:  M W KARAKASHIAN; J W HASTINGS
Journal:  J Gen Physiol       Date:  1963-09       Impact factor: 4.086

6.  RESTRICTION OF IN VIVO GENETIC TRANSCRIPTION TO ONE OF THE COMPLEMENTARY STRANDS OF DNA.

Authors:  M HAYASHI; M N HAYASHI; S SPIEGELMAN
Journal:  Proc Natl Acad Sci U S A       Date:  1963-10       Impact factor: 11.205

7.  CHROMATOGRAPHIC SEPARATION OF ANNEALED AND ENZYMATICALLY SYNTHESIZED RNA-DNA HYBRIDS.

Authors:  M N HAYASHI; M HAYASHI; S SPIEGELMAN
Journal:  Biophys J       Date:  1965-03       Impact factor: 4.033

8.  Conservation of a viral RNA genome during replication and translation.

Authors:  R H DOI; S SPIEGELMAN
Journal:  Proc Natl Acad Sci U S A       Date:  1963-03-15       Impact factor: 11.205

9.  Distinct cistrons for the two ribosomal RNA components.

Authors:  S A YANKOFSKY; S SPIEGELMAN
Journal:  Proc Natl Acad Sci U S A       Date:  1963-04       Impact factor: 11.205

10.  Ribonucleic acid and ribosomes of Bacillus stearothermophilus.

Authors:  G F Saunders; L L Campbell
Journal:  J Bacteriol       Date:  1966-01       Impact factor: 3.490

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