Literature DB >> 1393555

Electric-field-induced reconnection of severed axons.

A T Todorov1, D Yogev, P Qi, J H Fendler, G S Rodziewicz.   

Abstract

We report the first successful axon reconnection in the earthworm (Lumbricus terrestris) medial giant axon (MGA) by electric fields generated by electrical pulses of 10-100 microseconds duration and 80-200 V amplitude. Reconnection was documented by light and electron microscopy, and by transport of Lucifer yellow dye across the reconnected MGA segments. Direct repair of a severed nerve axon promises the advantages of preserving axon viability and distal connections.

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Year:  1992        PMID: 1393555     DOI: 10.1016/0006-8993(92)90151-x

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  5 in total

1.  Rapid induction of functional and morphological continuity between severed ends of mammalian or earthworm myelinated axons.

Authors:  A B Lore; J A Hubbell; D S Bobb; M L Ballinger; K L Loftin; J W Smith; M E Smyers; H D Garcia; G D Bittner
Journal:  J Neurosci       Date:  1999-04-01       Impact factor: 6.167

2.  A novel therapy to promote axonal fusion in human digital nerves.

Authors:  Ravinder Bamba; Thanapong Waitayawinyu; Ratnam Nookala; David Colton Riley; Richard B Boyer; Kevin W Sexton; Chinnakart Boonyasirikool; Sunyarn Niempoog; Nathaniel D Kelm; Mark D Does; Richard D Dortch; Robert Bruce Shack; Wesley P Thayer
Journal:  J Trauma Acute Care Surg       Date:  2016-11       Impact factor: 3.313

Review 3.  The curious ability of polyethylene glycol fusion technologies to restore lost behaviors after nerve severance.

Authors:  G D Bittner; D R Sengelaub; R C Trevino; J D Peduzzi; M Mikesh; C L Ghergherehchi; T Schallert; W P Thayer
Journal:  J Neurosci Res       Date:  2015-11-03       Impact factor: 4.164

Review 4.  Effect of Acupuncture on the p38 Signaling Pathway in Several Nervous System Diseases: A Systematic Review.

Authors:  Tzu-Hsuan Wei; Ching-Liang Hsieh
Journal:  Int J Mol Sci       Date:  2020-06-30       Impact factor: 5.923

5.  Immediate Enhancement of Nerve Function Using a Novel Axonal Fusion Device After Neurotmesis.

Authors:  David Colton Riley; Richard B Boyer; Curt A Deister; Alonda C Pollins; Nancy L Cardwell; Nathaniel D Kelm; Mark D Does; Richard D Dortch; Ravinder Bamba; Robert Bruce Shack; Wesley P Thayer
Journal:  Ann Plast Surg       Date:  2017-12       Impact factor: 1.763

  5 in total

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