Literature DB >> 13918409

Genetical and geographic studies on isoniazid inactivation.

S SUNAHARA.   

Abstract

Rapid and slow inactivators of isoniazid are homozygotes, and intermediate inactivators are heterozygotes. There is no dominance between the two alleles. The chasm between Eskimos and Caucasians in isoniazid metabolism is bridged by our investigation of the races in the Far East.

Entities:  

Keywords:  ETHNOLOGY; ISONIAZID/metabolism

Mesh：

Substances：

Year:  1961        PMID： 13918409     DOI： 10.1126/science.134.3489.1530

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  37 in total

Review 1.  The use of ethnic metabolic portraiture for the choice of individual pharmacotherapy strategy as exemplified by N-acetylation and chronic liver diseases.

Authors:  L A Piruzyan; L A Radkevich; N V Morozova
Journal:  Dokl Biol Sci       Date:  2003 Jan-Feb

2.  The use of ethnic portraiture for predicting individual sensitivity to chemicals as exemplified by N-acetylation in cancer patients.

Authors:  L A Piruzjan; L A Radkevich; N V Morozova
Journal:  Dokl Biol Sci       Date:  2003 Sep-Oct

3.  Molecular genotyping of N-acetylation polymorphism to predict phenotype.

Authors:  M Mashimo; T Suzuki; M Abe; T Deguchi
Journal:  Hum Genet       Date:  1992 Sep-Oct       Impact factor: 4.132

Review 4.  Physiological metrology.

Authors:  L A Piruzyan
Journal:  Dokl Biol Sci       Date:  2005 Sep-Oct

Review 5.  Pharmacogenetics in drug regulation: promise, potential and pitfalls.

Authors:  Rashmi R Shah
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2005-08-29       Impact factor: 6.237

Review 6.  Ethnic differences in drug disposition and responsiveness.

Authors:  A J Wood; H H Zhou
Journal:  Clin Pharmacokinet       Date:  1991-05       Impact factor: 6.447

7.  Is there any difference between acetylator phenotypes in tuberculosis patients and healthy subjects?

Authors:  Hossein Khalili; Simin Dashti-Khavidaki; Mohsen Amini; Reza Mahjub; Mahboobeh Hajiabdolbaghi
Journal:  Eur J Clin Pharmacol       Date:  2010-03       Impact factor: 2.953

8.  Simultaneous analysis of dapsone and monoacetyldapsone employing high performance liquid chromatography: a rapid method for determination of acetylator phenotype.

Authors:  K Carr; J A Oates; A S Nies; R L Woosley
Journal:  Br J Clin Pharmacol       Date:  1978-11       Impact factor: 4.335

9.  N-acetylation phenotyping with dapsone in a mainland Chinese population.

Authors:  Y Horai; H H Zhou; L M Zhang; T Ishizaki
Journal:  Br J Clin Pharmacol       Date:  1988-01       Impact factor: 4.335

10.  Genetic basis for a lower prevalence of deficient CYP2D6 oxidative drug metabolism phenotypes in black Americans.

Authors:  W E Evans; M V Relling; A Rahman; H L McLeod; E P Scott; J S Lin
Journal:  J Clin Invest       Date:  1993-05       Impact factor: 14.808
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