| Literature DB >> 13918378 |
Abstract
Studies were carried out to test the hypothesis that a disturbance in proline or hydroxyproline metabolism, or both, is associated with defective collagen formation in osteogenesis imperfecta, a generalized disorder of connective tissue. Oral tolerance for proline in affected patients was lower than in comparable controls.Entities:
Keywords: OSTEOGENESIS IMPERFECTA/nutrition and diet; PROLINE/nutrition and diet
Mesh：
Substances：
Year: 1961 PMID： 13918378 DOI： 10.1126/science.134.3489.1527
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728