Literature DB >> 13867194

Interactions of sympathomimetic drugs and their antagonists on the isolated atrium.

B G BENFEY, K GREEFF.   

Abstract

In the isolated guinea-pig atrium, phenoxybenzamine and other antagonists of sympathomimetic drugs and the adrenergic nerve blocking agent guanethidine inhibited the action of butyrylcholine and tyramine and potentiated the action of noradrenaline. Also in the isolated guinea-pig atrium, phenoxybenzamine and cocaine abolished the parasympathetic, and potentiated the sympathetic, effects of vagus stimulation.

Entities:  

Keywords:  HEART/pharmacology; SYMPATHOLYTICS/pharmacology; SYMPATHOMIMETICS/pharmacology

Mesh:

Substances:

Year:  1961        PMID: 13867194      PMCID: PMC1482051          DOI: 10.1111/j.1476-5381.1961.tb01283.x

Source DB:  PubMed          Journal:  Br J Pharmacol Chemother        ISSN: 0366-0826


  7 in total

1.  [Anaphylactic reactions in the isolated guinea pig auricle preparation and their influencing by antihistaminics. BOL, dihydroergotamine and reserpine].

Authors:  K GREEFF; B G BENFEY; A BOKELMANN
Journal:  Naunyn Schmiedebergs Arch Exp Pathol Pharmakol       Date:  1959

2.  [General physiology of neural and humoral regulation of the circulation].

Authors:  P HOLTZ
Journal:  Verh Dtsch Ges Kreislaufforsch       Date:  1959

3.  The effect on the isolated rabbit heart of vagal stimulation and its modification by cocaine, hexamethonium and ouabain.

Authors:  L M MCEWEN
Journal:  J Physiol       Date:  1956-03-28       Impact factor: 5.182

4.  [Experiments with acetylcholine, propionylcholine and butyrylcholine on isolated heart auricle preparation].

Authors:  P HOLTZ; E WESTERMANN
Journal:  Naunyn Schmiedebergs Arch Exp Pathol Pharmakol       Date:  1955

5.  Dibenamine blockade in strips of rabbit aorta and its use in differentiating receptors.

Authors:  R F FURCHGOTT
Journal:  J Pharmacol Exp Ther       Date:  1954-07       Impact factor: 4.030

6.  Isolated rabbit atria with sympathetic nerve supply.

Authors:  S HUKOVIC
Journal:  Br J Pharmacol Chemother       Date:  1959-09

7.  The action of sympathetic blocking agents on isolated and innervated atria and vessels.

Authors:  S HUKOVIC
Journal:  Br J Pharmacol Chemother       Date:  1960-03
  7 in total
  10 in total

1.  INHIBITION OF SYMPATHOMIMETIC EFFECTS ON THE HEART.

Authors:  B G BENFEY; D R VARMA
Journal:  Br J Pharmacol Chemother       Date:  1964-10

2.  Antisympathomimetic and antifibrillatory effects of pronethalol and propranolol.

Authors:  B G Benfey; D R Varma
Journal:  Br J Pharmacol Chemother       Date:  1966-01

3.  Alpha adrenergic contributions to dysrhythmia during myocardial ischemia and reperfusion in cats.

Authors:  D J Sheridan; P A Penkoske; B E Sobel; P B Corr
Journal:  J Clin Invest       Date:  1980-01       Impact factor: 14.808

4.  Supersensitivity to catecholamines following guanethidine.

Authors:  S D Gokhale; O D Gulati; V V Kelkar
Journal:  Br J Pharmacol Chemother       Date:  1967-08

5.  Interactions of sympathomimetic drugs, propranolol and phentolamine, on atrial refractory period and contractility.

Authors:  B G Benfey; D R Varma
Journal:  Br J Pharmacol Chemother       Date:  1967-08

6.  Presynaptic effect of clonidine antagonized by the tetramine disulphide, benextramine.

Authors:  B Belleau; B G Benfey; C Melchiorre
Journal:  Br J Pharmacol       Date:  1982-04       Impact factor: 8.739

7.  Inhibition by the tetramine disulphide, benextramine, of cardiac chronotropic histamine H2-receptor-mediated effects.

Authors:  B Belleau; B G Benfey; T J Benfey; C Melchiorre
Journal:  Br J Pharmacol       Date:  1982-04       Impact factor: 8.739

8.  Mechanism of action of guanethidine.

Authors:  K KADZIELAWA
Journal:  Br J Pharmacol Chemother       Date:  1962-08

9.  Dissociation of 5-hydroxytryptamine effects on myocardial contractility and cyclic AMP accumulation.

Authors:  B G Benfey; J Cohen; G Kunos; I Vermes-Kunos
Journal:  Br J Pharmacol       Date:  1974-04       Impact factor: 8.739

10.  Antagonism of acetylcholine by adrenaline antagonists.

Authors:  B G BENFEY; S A GRILLO
Journal:  Br J Pharmacol Chemother       Date:  1963-06
  10 in total

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