| Literature DB >> 13857 |
Abstract
A form of prothrombin induced by Warfarin therapy, has been isolated which is adsorbed onto insoluble barium salts, but has a reduced biological activity. This protein contains, on average, seven out of a possible ten gamma-carboxy glutamic acid residues. A second form of prothrombin is also described, which is not adsorbed into barium slats, and has less than 1% the activity of the normal protein, contains only four gamma-carboxy glutamic acid residues. The significance of these results is discussed.Entities:
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Year: 1977 PMID： 13857 DOI： 10.1016/0005-2795(77)90023-x
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002