Literature DB >> 1385006

Nitric oxide synthase in cardiac nerve fibers and neurons of rat and guinea pig heart.

L Klimaschewski1, W Kummer, B Mayer, J Y Couraud, U Preissler, B Philippin, C Heym.   

Abstract

Participation of nitric oxide (NO) in the autonomic innervation of rat and guinea pig hearts was investigated by applying the NADPH diaphorase technique and immunohistochemistry with NO synthase antiserum. We present evidence that NO synthase is localized in cardiac ganglion cells and nerve fibers innervating the sinuatrial and atrioventricular nodes, the myocardium, local neurons, coronary arteries, and pulmonary vessels, suggesting an involvement of NO in neurogenic heart rate regulation, myocardial cell function, neuronal transmission in cardiac ganglia, and coronary as well as pulmonary vasodilation.

Entities:  

Mesh：

Substances：

Year:  1992        PMID： 1385006     DOI： 10.1161/01.res.71.6.1533

Source DB:  PubMed          Journal:  Circ Res        ISSN： 0009-7330            Impact factor:   17.367


  33 in total

Review 1.  Myths and realities of the cardiac vagus.

Authors:  J H Coote
Journal:  J Physiol       Date:  2013-07-22       Impact factor: 5.182

2.  Mechanism of 5-hydroxytryptamine-induced coronary vasodilation assessed by direct detection of nitric oxide production in guinea-pig isolated heart.

Authors:  A J Ellwood; M J Curtis
Journal:  Br J Pharmacol       Date:  1996-10       Impact factor: 8.739

3.  Local cardiac effects of substance P: roles of acetylcholine and noradrenaline.

Authors:  H Chiao; R W Caldwell
Journal:  Br J Pharmacol       Date:  1995-01       Impact factor: 8.739

4.  Localisation of nitric oxide synthase and its colocalisation with vasoactive peptides in coronary and femoral arteries. An electron microscope study.

Authors:  K Dikranian; A Loesch; G Burnstock
Journal:  J Anat       Date:  1994-06       Impact factor: 2.610

5.  Ultrastructural investigation of nitric oxide synthase-immunoreactive nerves associated with coronary blood vessels of rat and guinea-pig.

Authors:  A A Sosunov; C J Hassall; A Loesch; M Turmaine; G Burnstock
Journal:  Cell Tissue Res       Date:  1995-06       Impact factor: 5.249

6.  NADPH diaphorase and nitric oxide synthase are expressed by the majority of intramural neurons in the neonatal guinea pig urinary bladder.

Authors:  M J Saffrey; C J Hassall; E W Moules; G Burnstock
Journal:  J Anat       Date:  1994-12       Impact factor: 2.610

7.  Ultrastructural localisation of nitric oxide synthase, endothelin and binding sites of lectin (from Bandeirea simplicifolia) in the rat carotid artery after balloon catheter injury.

Authors:  A Loesch; P Milner; S C Anglin; R Crowe; S Miah; J R McEwan; G Burnstock
Journal:  J Anat       Date:  1997-01       Impact factor: 2.610

8.  Characteristics of nitric oxide-mediated cholinergic modulation of calcium current in rabbit sino-atrial node.

Authors:  X Han; L Kobzik; D Severson; Y Shimoni
Journal:  J Physiol       Date:  1998-06-15       Impact factor: 5.182

9.  The distribution and co-localization of immunoreactivity to nitric oxide synthase, vasoactive intestinal polypeptide and substance P within nerve fibres supplying bovine and porcine female genital organs.

Authors:  M Majewski; W Sienkiewicz; J Kaleczyc; B Mayer; K Czaja; M Lakomy
Journal:  Cell Tissue Res       Date:  1995-09       Impact factor: 5.249

10.  Evidence for the involvement of both ATP and nitric oxide in non-adrenergic, non-cholinergic inhibitory neurotransmission in the rabbit portal vein.

Authors:  A L Brizzolara; R Crowe; G Burnstock
Journal:  Br J Pharmacol       Date:  1993-07       Impact factor: 8.739
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.