| Literature DB >> 1381221 |
A Rasola1, L J Galietta, D C Gruenert, G Romeo.
Abstract
The ion selectivity of swelling-activated Cl- currents has been investigated in three different human epithelial cell lines, two derived from the airway epithelium (9HTEo- and CFNPE9o-) and one from a colon carcinoma (T84). The relative permeability of volume-sensitive currents with respect to Cl- is: I- (1.19) greater than NO3- (1.07) approximately Br-(1.05) greater than Cl-(1.0) greater than F-(0.5) approximately HCO3-(0.48) greater than isethionate(0.28) greater than aspartate (0.14) approximately gluconate(0.13) approximately SO4(2-)(0.12). This type of ion selectivity is similar to that described for depolarization-activated outwardly rectifying Cl- channels found in epithelial cells.Entities:
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Year: 1992 PMID： 1381221 DOI： 10.1016/0925-4439(92)90108-y
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002