Literature DB >> 1379501

GABAA receptor channels: from subunits to functional entities.

W Wisden1, P H Seeburg.   

Abstract

GABAA receptor channels mediate postsynaptic inhibition. The functional diversity of these receptors rests on differences in subunit composition and on a large repertoire of subunits. Subunit expression patterns in the brain have been found to predict in vivo compositions of GABAA receptors. In addition, molecular determinants underlying the differential binding properties of allosteric ligands to receptor subtypes have been identified.

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Year:  1992        PMID： 1379501     DOI： 10.1016/0959-4388(92)90113-y

Source DB:  PubMed          Journal:  Curr Opin Neurobiol        ISSN： 0959-4388            Impact factor:   6.627


  39 in total

1.  The expression of GABA(A) receptor subunits in the substantia nigra is developmentally regulated and region-specific.

Authors:  J Velísková; H Kubová; L K Friedman; R Wu; E F Sperber; R S Zukin; S L Moshé
Journal:  Ital J Neurol Sci       Date:  1998-08

2.  DBI mRNA is expressed in endocrine pancreas and its post-translational product DBI(33-50) inhibits insulin release.

Authors:  P Borboni; R Magnaterra; O Porzio; A Fusco; G Sesti; A Bertoli; R Lauro; L N Marlier
Journal:  Endocrine       Date:  1995-04       Impact factor: 3.633

3.  Distribution and quantitative detection of GABAA receptor in Carassius auratus gibelio.

Authors:  Jiming Ruan; Kun Hu; Haixin Zhang; Yi Wang; Ailing Zhou; Yini Zhao; Xianle Yang
Journal:  Fish Physiol Biochem       Date:  2014-04-01       Impact factor: 2.794

Review 4.  GABAA receptors, anesthetics and anticonvulsants in brain development.

Authors:  Oliver Henschel; Keith E Gipson; Angelique Bordey
Journal:  CNS Neurol Disord Drug Targets       Date:  2008-04       Impact factor: 4.388

5.  Unique allosteric regulation of 5-hydroxytryptamine receptor-mediated signal transduction by oleamide.

Authors:  E A Thomas; M J Carson; M J Neal; J G Sutcliffe
Journal:  Proc Natl Acad Sci U S A       Date:  1997-12-09       Impact factor: 11.205

6.  The modulatory action of loreclezole at the gamma-aminobutyric acid type A receptor is determined by a single amino acid in the beta 2 and beta 3 subunit.

Authors:  P B Wingrove; K A Wafford; C Bain; P J Whiting
Journal:  Proc Natl Acad Sci U S A       Date:  1994-05-10       Impact factor: 11.205

7.  Benzodiazepine-insensitive mice generated by targeted disruption of the gamma 2 subunit gene of gamma-aminobutyric acid type A receptors.

Authors:  U Günther; J Benson; D Benke; J M Fritschy; G Reyes; F Knoflach; F Crestani; A Aguzzi; M Arigoni; Y Lang; H Bluethmann; H Mohler; B Lüscher
Journal:  Proc Natl Acad Sci U S A       Date:  1995-08-15       Impact factor: 11.205

8.  Whole-cell and single-channel currents activated by GABA and glycine in granule cells of the rat cerebellum.

Authors:  M Kaneda; M Farrant; S G Cull-Candy
Journal:  J Physiol       Date:  1995-06-01       Impact factor: 5.182

9.  The neurochemical pathology of thiamine deficiency: GABAA and glutamateNMDA receptor binding sites in a goat model.

Authors:  P R Dodd; G J Thomas; A McCloskey; D I Crane; I D Smith
Journal:  Metab Brain Dis       Date:  1996-03       Impact factor: 3.584

Review 10.  [Significance of GABAA receptors for the pathophysiology and therapy of panic disorders].

Authors:  R Rupprecht; P Zwanzger
Journal:  Nervenarzt       Date:  2003-06-24       Impact factor: 1.214
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