Literature DB >> 13787564

Effects of phenylalanine diet on brain serotonin in the rat.

A YUWILER, R T LOUTTIT.   

Abstract

Hooded rats fed diets rich in phenylalanine showed poorer performance on the Hebb-Williams maze than controls, as well as decreased brain serotonin levels. There did not appear to be a causal relationship between these findings, and the findings do not appear to be attributable either to a generalized behavioral defect or to inadequate dietary intake.

Entities:  

Keywords:  BRAIN/metabolism; PHENYLALANINE/nutrition and diet; SEROTONIN/metabolism

Mesh:

Substances:

Year:  1961        PMID: 13787564     DOI: 10.1126/science.134.3482.831

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  3 in total

1.  Histidinaemia.

Authors:  J W Seakins; J B Holton
Journal:  Biochem J       Date:  1969-02       Impact factor: 3.857

2.  Serotonin in experimental histidinemia.

Authors:  O Douay; P P Kamoun
Journal:  Neurochem Res       Date:  1980-08       Impact factor: 3.996

3.  Tryptophan metabolism in a patient with phenylketonuria and scleroderma: a proposed explanation of the indole defect in phenylketonuria.

Authors:  K N Drummond; A F Michael; R A Good
Journal:  Can Med Assoc J       Date:  1966-04-16       Impact factor: 8.262

  3 in total

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