| Literature DB >> 1378302 |
A E el-Husseini1, J A Paterson, Y Myal, R P Shiu.
Abstract
We utilized the reverse transcription-polymerase chain reaction (RT-PCR) to detect the presence of basic fibroblast growth factor (bFGF) messenger RNA in rat brain, ovary and kidney. The nucleotide sequence of the RT-PCR product revealed a novel 3' untranslated (UT) sequence in the rat basic FGF mRNA. In this sequence, as in the 3' UT regions of many growth regulatory genes, there is a high degree of conservation of A+T rich motifs which have been shown to play a major role in mRNA stability.Entities:
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Year: 1992 PMID： 1378302 DOI： 10.1016/0167-4781(92)90031-t
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002