Literature DB >> 1376173

A point mutation in a Shaker K+ channel changes its charybdotoxin binding site from low to high affinity.

S A Goldstein1, C Miller.   

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Year:  1992        PMID： 1376173      PMCID： PMC1260466          DOI： 10.1016/S0006-3495(92)81760-5

Source DB:  PubMed          Journal:  Biophys J        ISSN： 0006-3495            Impact factor:   4.033


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  10 in total

1.  Mutations affecting TEA blockade and ion permeation in voltage-activated K+ channels.

Authors:  R MacKinnon; G Yellen
Journal:  Science       Date:  1990-10-12       Impact factor: 47.728

2.  Mapping the receptor site for charybdotoxin, a pore-blocking potassium channel inhibitor.

Authors:  R MacKinnon; L Heginbotham; T Abramson
Journal:  Neuron       Date:  1990-12       Impact factor: 17.173

3.  Design, synthesis, and functional expression of a gene for charybdotoxin, a peptide blocker of K+ channels.

Authors:  C S Park; S F Hausdorff; C Miller
Journal:  Proc Natl Acad Sci U S A       Date:  1991-03-15       Impact factor: 11.205

4.  Sequence of a probable potassium channel component encoded at Shaker locus of Drosophila.

Authors:  B L Tempel; D M Papazian; T L Schwarz; Y N Jan; L Y Jan
Journal:  Science       Date:  1987-08-14       Impact factor: 47.728

5.  Rapid and efficient site-specific mutagenesis without phenotypic selection.

Authors:  T A Kunkel
Journal:  Proc Natl Acad Sci U S A       Date:  1985-01       Impact factor: 11.205

6.  Functional characterization of a minimal K+ channel expressed from a synthetic gene.

Authors:  S F Hausdorff; S A Goldstein; E E Rushin; C Miller
Journal:  Biochemistry       Date:  1991-04-02       Impact factor: 3.162

7.  Three-dimensional structure of natural charybdotoxin in aqueous solution by 1H-NMR. Charybdotoxin possesses a structural motif found in other scorpion toxins.

Authors:  F Bontems; C Roumestand; P Boyot; B Gilquin; Y Doljansky; A Menez; F Toma
Journal:  Eur J Biochem       Date:  1991-02-26

8.  Competition for block of a Ca2(+)-activated K+ channel by charybdotoxin and tetraethylammonium.

Authors:  C Miller
Journal:  Neuron       Date:  1988-12       Impact factor: 17.173

9.  Molecular basis of functional diversity of voltage-gated potassium channels in mammalian brain.

Authors:  W Stühmer; J P Ruppersberg; K H Schröter; B Sakmann; M Stocker; K P Giese; A Perschke; A Baumann; O Pongs
Journal:  EMBO J       Date:  1989-11       Impact factor: 11.598

10.  Mechanism of charybdotoxin block of the high-conductance, Ca2+-activated K+ channel.

Authors:  R MacKinnon; C Miller
Journal:  J Gen Physiol       Date:  1988-03       Impact factor: 4.086
  10 in total
  20 in total

1.  Revisiting the role of Ca2+ in Shaker K+ channel gating.

Authors:  K H Hong; C M Armstrong; C Miller
Journal:  Biophys J       Date:  2001-05       Impact factor: 4.033

2.  Slow inactivation in voltage gated potassium channels is insensitive to the binding of pore occluding peptide toxins.

Authors:  Carolina Oliva; Vivian González; David Naranjo
Journal:  Biophys J       Date:  2005-05-27       Impact factor: 4.033

3.  Electrostatic distance geometry in a K+ channel vestibule.

Authors:  M Stocker; C Miller
Journal:  Proc Natl Acad Sci U S A       Date:  1994-09-27       Impact factor: 11.205

4.  Characterization of apamin-sensitive Ca(2+)-activated potassium channels in human leukaemic T lymphocytes.

Authors:  C Hanselmann; S Grissmer
Journal:  J Physiol       Date:  1996-11-01       Impact factor: 5.182

5.  Stabilization of the conductive conformation of a voltage-gated K+ (Kv) channel: the lid mechanism.

Authors:  Jose S Santos; Ruhma Syeda; Mauricio Montal
Journal:  J Biol Chem       Date:  2013-04-22       Impact factor: 5.157

6.  Domain structure and conformational changes in rat KV2.1 ion channel.

Authors:  Anastasia Grizel; Anna Popinako; Marina A Kasimova; Louisa Stevens; Maria Karlova; Mikhail M Moisenovich; Olga S Sokolova
Journal:  J Neuroimmune Pharmacol       Date:  2014-09-26       Impact factor: 4.147

7.  Proton probing of the charybdotoxin binding site of Shaker K+ channels.

Authors:  P Perez-Cornejo; P Stampe; T Begenisich
Journal:  J Gen Physiol       Date:  1998-03       Impact factor: 4.086

8.  A marine snail neurotoxin shares with scorpion toxins a convergent mechanism of blockade on the pore of voltage-gated K channels.

Authors:  E García; M Scanlon; D Naranjo
Journal:  J Gen Physiol       Date:  1999-07       Impact factor: 4.086

9.  Nano-positioning system for structural analysis of functional homomeric proteins in multiple conformations.

Authors:  H Clark Hyde; Walter Sandtner; Ernesto Vargas; Alper T Dagcan; Janice L Robertson; Benoit Roux; Ana M Correa; Francisco Bezanilla
Journal:  Structure       Date:  2012-10-10       Impact factor: 5.006

10.  Conformational changes in the C terminus of Shaker K+ channel bound to the rat Kvbeta2-subunit.

Authors:  Olga Sokolova; Alessio Accardi; David Gutierrez; Adrian Lau; Mike Rigney; Nikolaus Grigorieff
Journal:  Proc Natl Acad Sci U S A       Date:  2003-10-20       Impact factor: 11.205
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