| Literature DB >> 1375448 |
M E Sarciron1, I Delabre, S Walbaum, G Raynaud, A F Petavy.
Abstract
Isoprinosine was given at daily doses of 0.5, 1, 2, and 4 g kg-1 of body weight to jirds that were infected for 3 months with Echinococcus multilocularis metacestodes. The effects of the different drug doses on metacestodes were studied by transmission electron microscopy and biochemical methods. At lower doses, increases in uric acid and adenosine deaminase activity were noted. At 4 g kg-1 of body weight, marked ultrastructural damage with metabolic perturbations was observed.Entities:
Mesh：
Substances：
Year: 1992 PMID： 1375448 PMCID： PMC189252 DOI： 10.1128/AAC.36.1.191
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191