Literature DB >> 1372445

Cloning of a D-type cyclin from murine erythroleukemia cells.

H Kiyokawa1, X Busquets, C T Powell, L Ngo, R A Rifkind, P A Marks.   

Abstract

We report the complete coding sequence of a cDNA, designated CYL2, derived from a murine erythroleukemia cell library. CYL2 is considered to encode a D-type cyclin because (i) there is cross hybridization with CYL1 (a murine homolog of human cyclin D1) and the encoded protein has 64% amino acid sequence identity with CYL1 and (ii) murine erythroleukemia cell-derived CYL2 contains an amino acid sequence identical to that previously reported for the C-terminal portion of a partially sequenced CYL2. Transcripts of murine erythroleukemia cell CYL2 undergo alternative polyadenylylation like that of human cyclin D1. A major 6.5-kilobase CYL2 transcript changes its expression during the cell cycle with a broad peak through G1 and S phases and a decrease in G2/M phases. The present findings suggest that CYL2 plays a role in the G1 to S phase progression.

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Year:  1992        PMID： 1372445      PMCID： PMC48674          DOI： 10.1073/pnas.89.6.2444

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  41 in total

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Authors:  Y Xiong; T Connolly; B Futcher; D Beach
Journal:  Cell       Date:  1991-05-17       Impact factor: 41.582

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Journal:  Cell       Date:  1991-09-20       Impact factor: 41.582
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  22 in total

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Authors:  S Mai; J Hanley-Hyde; G J Rainey; T I Kuschak; J T Paul; T D Littlewood; H Mischak; L M Stevens; D W Henderson; J F Mushinski
Journal:  Neoplasia       Date:  1999-08       Impact factor: 5.715

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Journal:  Mol Cell Biol       Date:  1998-06       Impact factor: 4.272

Review 3.  Alternative poly(A) site selection in complex transcription units: means to an end?

Authors:  G Edwalds-Gilbert; K L Veraldi; C Milcarek
Journal:  Nucleic Acids Res       Date:  1997-07-01       Impact factor: 16.971

4.  Gris1, a new common integration site in Graffi murine leukemia virus-induced leukemias: overexpression of a truncated cyclin D2 due to alternative splicing.

Authors:  Catherine Denicourt; Christine A Kozak; Eric Rassart
Journal:  J Virol       Date:  2003-01       Impact factor: 5.103

5.  Genetic replacement of cyclin D1 function in mouse development by cyclin D2.

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6.  Differential effect of H1 variant overexpression on cell cycle progression and gene expression.

Authors:  D T Brown; B T Alexander; D B Sittman
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7.  Growth-regulated expression of D-type cyclin genes in human diploid fibroblasts.

Authors:  K A Won; Y Xiong; D Beach; M Z Gilman
Journal:  Proc Natl Acad Sci U S A       Date:  1992-10-15       Impact factor: 11.205

Review 8.  The cell cycle and the retinoblastoma protein family.

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9.  Hexamethylenebisacetamide-induced erythroleukemia cell differentiation involves modulation of events required for cell cycle progression through G1.

Authors:  H Kiyokawa; V M Richon; G Venta-Perez; R A Rifkind; P A Marks
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Review 10.  Inducing differentiation of transformed cells with hybrid polar compounds: a cell cycle-dependent process.

Authors:  P A Marks; V M Richon; H Kiyokawa; R A Rifkind
Journal:  Proc Natl Acad Sci U S A       Date:  1994-10-25       Impact factor: 11.205
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