Literature DB >> 13709962

Bilirubin and urobilins in germfree, ex-germfree, and conventional rats.

B E GUSTAFSSON, L S LANKE.   

Abstract

No urobilinogens are present in the feces or urine of germfree rats. After contamination of germfree animals with feces from conventional animals the exgermfree rats produced urobilins to the same extent as conventional animals on the same diet. The negative urobilin test turned positive in germfree animals infected with a single Clostridium-like microorganism isolated from the intestinal contents of rats with urobilins in the feces. The output increased in these monoinfected animals after superinfection with a strain of E. coli but never reached the values of conventional animals.

Entities:  

Keywords:  BILIRUBIN/metabolism; GERM-FREE LIFE; UROBILIN/metabolism

Mesh：

Substances：

Year:  1960        PMID： 13709962      PMCID： PMC2137325          DOI： 10.1084/jem.112.6.975

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  5 in total

1.  Lightweight stainless steel systems for rearing germfree animals.

Authors:  B E GUSTAFSSON
Journal:  Ann N Y Acad Sci       Date:  1959-05-08       Impact factor: 5.691

2.  Vitamin K deficiency in germfree rats.

Authors:  B E GUSTAFSSON
Journal:  Ann N Y Acad Sci       Date:  1959-05-08       Impact factor: 5.691

3.  Composition of the urobilin group in urine bile, and feces and the significance of variations in health and disease.

Authors:  C J WATSON; M WEIMER
Journal:  J Lab Clin Med       Date:  1959-07

4.  Seminar: the pyrrol pigments and hemoglobin catabolism.

Authors:  C J WATSON
Journal:  Minn Med       Date:  1956-05

5.  A note on the disturbance of the haemoglobin metabolism of the rat by sulphanilamide.

Authors:  J W Legge
Journal:  Biochem J       Date:  1949       Impact factor: 3.857
  5 in total
  8 in total

1.  INTESTINAL ABSORPTION OF BILE PIGMENTS. 3. THE ENTEROHEPATIC CIRCULATION OF UROBILINOGEN IN THE RAT.

Authors:  R LESTER; R SCHMID
Journal:  J Clin Invest       Date:  1965-05       Impact factor: 14.808

2.  Recent studies of the urobilin problem.

Authors:  C J WATSON
Journal:  J Clin Pathol       Date:  1963-01       Impact factor: 3.411

Review 3.  Bilirubin in the Liver-Gut Signaling Axis.

Authors:  Abdul-Rizaq Hamoud; Lauren Weaver; David E Stec; Terry D Hinds
Journal:  Trends Endocrinol Metab       Date:  2018-02-03       Impact factor: 12.015

4.  Mechanisms of renal excretion of urobilinogen.

Authors:  E Bourke; M D Milne; G S Stokes
Journal:  Br Med J       Date:  1965-12-25

Review 5.  The gnotobiotic animal as a tool in the study of host microbial relationships.

Authors:  H A Gordon; L Pesti
Journal:  Bacteriol Rev       Date:  1971-12

6.  On the existence of a mono-vinyl d-urobilin.

Authors:  M Chedekel; F A Bovey; A I Brewster; Z J Petryka; M Weimer; C J Watson; A Moscowitz; D A Lightner
Journal:  Proc Natl Acad Sci U S A       Date:  1974-05       Impact factor: 11.205

7.  Intestinal microbiota regulate xenobiotic metabolism in the liver.

Authors:  Britta Björkholm; Chek Mei Bok; Annelie Lundin; Joseph Rafter; Martin Lloyd Hibberd; Sven Pettersson
Journal:  PLoS One       Date:  2009-09-09       Impact factor: 3.240

8.  Autoantibodies to colon in germfree rats monocontaminated with Clostridium difficile.

Authors:  S Hammarström; P Perlmann; B E Gustafsson; R Lagercrantz
Journal:  J Exp Med       Date:  1969-04-01       Impact factor: 14.307
  8 in total

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