Literature DB >> 13699770

Effects of deoxyribonucleic acid products on deoxyribonucleic acid synthesis of virulent and avirulent pneumococci.

W FIRSHEIN.   

Abstract

Firshein, W. (Wesleyan University, Middletown, Conn.). Effects of deoxyribonucleic acid products on deoxyribonucleic acid synthesis of virulent and avirulent pneumococci. J. Bacteriol. 82:169-180. 1961.-Cell suspensions of virulent pneumococci synthesize a greater amount of deoxyribonucleic acid (DNA) per cell in the presence of DNA + deoxyribonuclease + mixtures of deoxynucleosides and deoxynucleotides (supplement-1) than unsupplemented suspensions. Under identical conditions, avirulent and weakly virulent pneumococci do not respond to these DNA breakdown products. Glucose and casitone must be present for maximal effects to occur.A DNA turnover occurs in virulent cells. This has been demonstrated by a decrease in specific activity of H(3)-DNA extracted from virulent (S) cells exposed to nonradioactive supplement-1.

Entities:  

Keywords:  DESOXYRIBONUCLEIC ACID/metabolism; DIPLOCOCCUS PNEUMONIAE/metabolism

Mesh：

Substances：

Year:  1961        PMID： 13699770      PMCID： PMC279139          DOI： 10.1128/jb.82.2.169-180.1961

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  20 in total

1.  The synthesis of type III pneumococcal capsular polysaccharide from uridine nucleotides by a cell-free extract of Diplococcus pneumoniae type III.

Authors:  E E SMITH; G T MILLS; H P BERNHEIMER; R AUSTRIAN
Journal:  J Biol Chem       Date:  1960-07       Impact factor: 5.157

2.  Effects of deoxyribonucleic acid products on respiration of virulent and avirulent pneumococci.

Authors:  W FIRSHEIN
Journal:  J Bacteriol       Date:  1961-08       Impact factor: 3.490

3.  The restoration of hemolysin formation in x-rayed rabbits by nucleic acid derivatives and antagonists of nucleic acid synthesis.

Authors:  W H TALIAFERRO; B N JAROSLOW
Journal:  J Infect Dis       Date:  1960 Nov-Dec       Impact factor: 5.226

4.  The metabolic stability of rat liver deoxyribonucleic acid: a turnover study.

Authors:  J R FRESCO; A BENDICH
Journal:  J Biol Chem       Date:  1960-04       Impact factor: 5.157

5.  The metabolic stability of nucleic acids in Escherichia coli.

Authors:  A F GRAHAM; L SIMINOVITCH
Journal:  Can J Microbiol       Date:  1956-10       Impact factor: 2.419

6.  THE SYNTHESIS OF NUCLEIC ACIDS IN CULTURES OF ESCHERICHIA COLI, STRAINS B AND B/R.

Authors:  M L Morse; C E Carter
Journal:  J Bacteriol       Date:  1949-09       Impact factor: 3.490

7.  ON THE NATURE OF THE SELECTIVE EFFECTS OF DEOXYRIBONUCLEIC ACID DIGESTS UPON PNEUMOCOCCI OF DIFFERENT VIRULENCE.

Authors:  W Firshein; W Braun
Journal:  Proc Natl Acad Sci U S A       Date:  1958-09-15       Impact factor: 11.205

8.  The purine and pyrimidine composition of deoxypentose nucleic acids.

Authors:  G R WYATT
Journal:  Biochem J       Date:  1951-05       Impact factor: 3.857

9.  Crystalline desoxyribonuclease; isolation and general properties; spectrophotometric method for the measurement of desoxyribonuclease activity.

Authors:  M KUNITZ
Journal:  J Gen Physiol       Date:  1950-03       Impact factor: 4.086

10.  Conservation of nucleic acids during bacterial growth.

Authors:  A D HERSHEY
Journal:  J Gen Physiol       Date:  1954-11-20       Impact factor: 4.086
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  10 in total

1.  Effect of manganese and enzymatic deoxyribonucleic acid digests on population changes and respiration of Pneumococci.

Authors:  W FIRSHEIN
Journal:  J Bacteriol       Date:  1962-09       Impact factor: 3.490

2.  Effects of deoxyribonucleic acid products on respiration of virulent and avirulent pneumococci.

Authors:  W FIRSHEIN
Journal:  J Bacteriol       Date:  1961-08       Impact factor: 3.490

3.  Inhibitors of preferentially stimulated deoxyribonucleic acid synthesis in pneumococci.

Authors:  W Firshein; W Braun
Journal:  J Bacteriol       Date:  1964-05       Impact factor: 3.490

Review 4.  Biodynamic effects of oligonucleotides.

Authors:  W Braun; W Firshein
Journal:  Bacteriol Rev       Date:  1967-06

5.  Population changes in Diplococcus pneumoniae.

Authors:  G CARTA; W FIRSHEIN
Journal:  J Bacteriol       Date:  1962-09       Impact factor: 3.490

6.  INFLUENCE OF DEOXYRIBONUCLEIC ACID DEGRADATION PRODUCTS AND ORTHOPHOSPHATE ON DEOXYNUCLEOTIDE KINASE ACTIVITY AND DEOXYRIBONUCLEIC ACID SYNTHESIS IN PNEUMOCOCCUS TYPE 3.

Authors:  W FIRSHEIN
Journal:  J Bacteriol       Date:  1965-08       Impact factor: 3.490

7.  INFLUENCE OF DEOXYRIBONUCLEIC ACID DEGRADATION PRODUCTS AND ORTHOPHOSPHATE ON UPTAKE OF DEOXYNUCLEOSIDES IN PNEUMOCOCCUS TYPE 3.

Authors:  W FIRSHEIN; B A GARGAN
Journal:  J Bacteriol       Date:  1965-08       Impact factor: 3.490

8.  Uptake of synthetic polynucleotides by competent cells of Bacillus subtilis.

Authors:  O Ciferri; S Barlati; J Lederberg
Journal:  J Bacteriol       Date:  1970-11       Impact factor: 3.490

9.  Differential effects of deoxyribonucleotides on respiration of virulent pneumococci.

Authors:  W Firshein; R J Erickson; B A Gargan
Journal:  J Bacteriol       Date:  1966-12       Impact factor: 3.490

10.  Enrichment of DNA polymerase III activity in a DNA membrane complex purified from Pneumococcus: the possible existence of subcomplexes.

Authors:  W Firshein; I W Gelman
Journal:  Mol Gen Genet       Date:  1981
  10 in total

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