Literature DB >> 1368935

Inducible vectors for expression in mammalian cells.

G T Yarranton1.   

Abstract

The most recent developments in mammalian cell inducible expression systems have involved the use of bacterial gene control elements and viral transactivator proteins. The combination of hybrid viral transactivator and bacterial repressor proteins, and simple chemical inducers can provide induction ratios of over 1000-fold. These developments will have applications in both cell-based research and the generation of transgenic animals.

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Year:  1992        PMID： 1368935     DOI： 10.1016/0958-1669(92)90078-w

Source DB:  PubMed          Journal:  Curr Opin Biotechnol        ISSN： 0958-1669            Impact factor:   9.740


  18 in total

1.  A novel drug-regulated gene expression system based on the nuclear receptor constitutive androstane receptor (CAR).

Authors:  P Honkakoski; I Jääskeläinen; M Kortelahti; A Urtti
Journal:  Pharm Res       Date:  2001-02       Impact factor: 4.200

2.  Creation of a reversible on/off system for site-specific in vivo control of exogenous gene activity in the renal glomerulus.

Authors:  M Kitamura
Journal:  Proc Natl Acad Sci U S A       Date:  1996-07-09       Impact factor: 11.205

3.  Inducible expression based on regulated recombination: a single vector strategy for stable expression in cultured cells.

Authors:  P O Angrand; C P Woodroofe; F Buchholz; A F Stewart
Journal:  Nucleic Acids Res       Date:  1998-07-01       Impact factor: 16.971

Review 4.  Recent advances in transgenic technology.

Authors:  E R Cameron
Journal:  Mol Biotechnol       Date:  1997-06       Impact factor: 2.695

5.  A conditional self-inactivating retrovirus vector that uses a tetracycline-responsive expression system.

Authors:  J J Hwang; L Li; W F Anderson
Journal:  J Virol       Date:  1997-09       Impact factor: 5.103

6.  A doxycycline-inducible, tissue-specific aromatase-expressing transgenic mouse.

Authors:  Jenny D Y Chow; John T Price; Margaret M Bills; Evan R Simpson; Wah Chin Boon
Journal:  Transgenic Res       Date:  2011-05-26       Impact factor: 2.788

7.  Novel retroviral vector transferring a suicide gene and a selectable marker gene with enhanced gene expression by using a tetracycline-responsive expression system.

Authors:  J J Hwang; Z Scuric; W F Anderson
Journal:  J Virol       Date:  1996-11       Impact factor: 5.103

8.  Dexamethasone inducible gene expression optimised by glucocorticoid antagonists.

Authors:  W Mikulits; D Chen; E W Müllner
Journal:  Nucleic Acids Res       Date:  1995-06-25       Impact factor: 16.971

9.  Rapid retroviral delivery of tetracycline-inducible genes in a single autoregulatory cassette.

Authors:  A Hofmann; G P Nolan; H M Blau
Journal:  Proc Natl Acad Sci U S A       Date:  1996-05-28       Impact factor: 11.205

10.  Promoters of cancer genes for recombinant protein expression in human cancer cell lines.

Authors:  Mohammad Pourhassan-Moghaddam; Behrouz Farhadi; Kazem Nejati-Koshki; Tamouchin Moharrami
Journal:  Bioimpacts       Date:  2012-03-17
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