Literature DB >> 1368302

Molecular stability of chicken and rabbit immunoglobulin G.

M Shimizu1, H Nagashima, K Sano, K Hashimoto, M Ozeki, K Tsuda, H Hatta.   

Abstract

Molecular stability of chicken egg yolk immunoglobulin G (IgY) and that of rabbit IgG were compared by measuring antibody activities and conformational changes. Stability of rabbit IgG to acid denaturation was much higher than that of IgY. Conformation of the IgY molecule was readily changed in acidic conditions, resulting in a rapid loss of antibody activity. Much less stable natures of IgY to heat-treatment and guanidine-HCl denaturation than rabbit IgG were also observed. Differences in the structure between the two immunoglobulins that might participate in their different stability were inferred from their amino acid sequence data. Importance of the intramolecular disulfide linkage in the rabbit light chain and some other structural differences were suggested.

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Year:  1992        PMID： 1368302     DOI： 10.1271/bbb.56.270

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN： 0916-8451            Impact factor:   2.043


  17 in total

1.  Anti-Pseudomonas aeruginosa IgY Antibodies Induce Specific Bacterial Aggregation and Internalization in Human Polymorphonuclear Neutrophils.

Authors:  K Thomsen; L Christophersen; T Bjarnsholt; P Ø Jensen; C Moser; N Høiby
Journal:  Infect Immun       Date:  2015-04-20       Impact factor: 3.441

2.  Preparation of egg yolk antibodies against BoNT/B and their passive protection in mouse models.

Authors:  Zherong You; Hao Yang; Wenwen Xin; Lin Kang; Shan Gao; Junhong Wang; Tao Zhang; Jinglin Wang
Journal:  Hum Vaccin Immunother       Date:  2014       Impact factor: 3.452

Review 3.  Oral delivery of antibodies. Future pharmacokinetic trends.

Authors:  R M Reilly; R Domingo; J Sandhu
Journal:  Clin Pharmacokinet       Date:  1997-04       Impact factor: 6.447

4.  Magnet Patterned Superparamagnetic Fe3 O4 /Au Core-Shell Nanoplasmonic Sensing Array for Label-Free High Throughput Cytokine Immunoassay.

Authors:  Yuxin Cai; Jingyi Zhu; Jiacheng He; Wen Yang; Chao Ma; Feng Xiong; Feng Li; Weiqiang Chen; Pengyu Chen
Journal:  Adv Healthc Mater       Date:  2019-01-15       Impact factor: 9.933

5.  Effect of methionine deficiency on duodenal and jejunal IgA+ B cell count and immunoglobulin level of broilers.

Authors:  B Wu; L Li; T Ruan; X Peng
Journal:  Iran J Vet Res       Date:  2018       Impact factor: 1.376

6.  Effects of soybean milk, chitosan, and anti-Streptococcus mutans IgY in malnourished rats' dental biofilm and the IgY persistency in saliva.

Authors:  Endang W Bachtiar; Retno D Soejoedono; Boy M Bachtiar; Alisya Henrietta; Nur Farhana; Mindya Yuniastuti
Journal:  Interv Med Appl Sci       Date:  2015-09-28

Review 7.  IgY antibodies in human nutrition for disease prevention.

Authors:  Sandra Müller; Andreas Schubert; Julia Zajac; Terry Dyck; Christopher Oelkrug
Journal:  Nutr J       Date:  2015-10-20       Impact factor: 3.271

8.  Toxicological effects of nickel chloride on IgA+ B Cells and sIgA, IgA, IgG, IgM in the intestinal mucosal immunity in broilers.

Authors:  Bangyuan Wu; Hengmin Cui; Xi Peng; Jing Fang; Zhicai Zuo; Junliang Deng; Jianying Huang
Journal:  Int J Environ Res Public Health       Date:  2014-08-11       Impact factor: 3.390

9.  The antigenicity and cholesteroid nature of mycolic acids determined by recombinant chicken antibodies.

Authors:  Heena Ranchod; Fortunate Ndlandla; Yolandy Lemmer; Mervyn Beukes; Johann Niebuhr; Juma Al-Dulayymi; Susan Wemmer; Jeanni Fehrsen; Mark Baird; Jan Verschoor
Journal:  PLoS One       Date:  2018-08-09       Impact factor: 3.240

Review 10.  IgY antibodies for the immunoprophylaxis and therapy of respiratory infections.

Authors:  Aymn Talat Abbas; Sherif Aly El-Kafrawy; Sayed Sartaj Sohrab; Esam Ibraheem Ahmed Azhar
Journal:  Hum Vaccin Immunother       Date:  2018-09-19       Impact factor: 3.452
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