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Literature DB >> 1368276

Complications of RNA heterogeneity for the engineering of virus vaccines and antiviral agents.

E Domingo¹, J J Holland.

Abstract

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Year: 1992 PMID： 1368276 DOI： 10.1007/978-1-4615-3424-2_2

Source DB: PubMed Journal: Genet Eng (N Y) ISSN： 0196-3716

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17 in total

Review 1. Viral quasispecies evolution.

Authors: Esteban Domingo; Julie Sheldon; Celia Perales
Journal: Microbiol Mol Biol Rev Date: 2012-06 Impact factor: 11.056

2. Exponential fitness gains of RNA virus populations are limited by bottleneck effects.

Authors: I S Novella; J Quer; E Domingo; J J Holland
Journal: J Virol Date: 1999-02 Impact factor: 5.103

3. Tempo and mode of inhibitor-mutagen antiviral therapies: a multidisciplinary approach.

Authors: Jaime Iranzo; Celia Perales; Esteban Domingo; Susanna C Manrubia
Journal: Proc Natl Acad Sci U S A Date: 2011-09-12 Impact factor: 11.205

4. Increased replicative fitness can lead to decreased drug sensitivity of hepatitis C virus.

Authors: Julie Sheldon; Nathan M Beach; Elena Moreno; Isabel Gallego; David Piñeiro; Encarnación Martínez-Salas; Josep Gregori; Josep Quer; Juan Ignacio Esteban; Charles M Rice; Esteban Domingo; Celia Perales
Journal: J Virol Date: 2014-08-13 Impact factor: 5.103

5. Efficient virus extinction by combinations of a mutagen and antiviral inhibitors.

Authors: N Pariente; S Sierra; P R Lowenstein; E Domingo
Journal: J Virol Date: 2001-10 Impact factor: 5.103

6. Extreme fitness differences in mammalian and insect hosts after continuous replication of vesicular stomatitis virus in sandfly cells.

Authors: I S Novella; D K Clarke; J Quer; E A Duarte; C H Lee; S C Weaver; S F Elena; A Moya; E Domingo; J J Holland
Journal: J Virol Date: 1995-11 Impact factor: 5.103

Complications of RNA heterogeneity for the engineering of virus vaccines and antiviral agents.

Review 1. Viral quasispecies evolution.

2. Exponential fitness gains of RNA virus populations are limited by bottleneck effects.

3. Tempo and mode of inhibitor-mutagen antiviral therapies: a multidisciplinary approach.

4. Increased replicative fitness can lead to decreased drug sensitivity of hepatitis C virus.

5. Efficient virus extinction by combinations of a mutagen and antiviral inhibitors.

6. Extreme fitness differences in mammalian and insect hosts after continuous replication of vesicular stomatitis virus in sandfly cells.

7. Recombinant oncolytic poliovirus eliminates glioma in vivo without genetic adaptation to a pathogenic phenotype.

8. Many-trillionfold amplification of single RNA virus particles fails to overcome the Muller's ratchet effect.

9. Preextinction viral RNA can interfere with infectivity.

10. Potential benefits of sequential inhibitor-mutagen treatments of RNA virus infections.